1458 results
Primary objectiveIs RRSO at age <= 45 in BRCA1/2 mutation carriers a risk factor for development of subclinical atherosclerosis, independent of traditional cardiovascular risk factors? Secondary objectiveAre menopausal symptoms in BRCA1/2…
Phase 1:- The main objective of this phase of the study is to determine the variation of UAC over 8 weeks time in toddlers. - The secondary objective of this phase is to determine the variation of UAC over 3 days time.Phase 2:- The main objective of…
The primary aim of the proposed study is to assess whether stenting for symptomatic vertebral artery stenosis >= 50% is feasible and safe. A secondary aim is to assess the rate of new vascular events in the territory of the vertebrobasilar…
The purpose of this clinical investigation is to verify the efficacy and safety of the CVRx Neo System in subjects who qualify for the implantation for a Baroreflex Activation Therapy System compared with subjects who do not receive this device.
The aim of this study is to determine the accumulation of nadroparin used in renal insufficient patients with VTE, by measuring anti-Xa levels.
1. To proof local delivery of intravenously administered liposomal glucocorticoids (Nanocort) in subjects with peripheral artery disease by demonstrating Nanocort in atherosclerotic tissue. 2. To determine the differences between cytokine production…
This study aims to evaluate the safety, tolerability and sedative proporties of a single dose of intransally administered dexmedetomidine in person odler than 65 years, differentiating between person using beta-blocking medication and those not…
The objective of the current study proposal is therefore to investigate *the origin of cerebral small vessel disease*
To investigate the in vitro effect of both pro- and anticoagulation therapy on thrombin generation by Calibrated Automated Thrombography in plasma from patients with cirrhosis undergoing liver transplantation.
To provide preliminary technical feasibility, safety and efficacy data foreCLIPs Family of products.
To validate and compare smartphone-connected blood pressure monitors produced by Withings, Qardio and iHealth with the gold standard and a validated automatic blood pressure monitor.
The primary efficacy objective of the study is:* to evaluate whether rivaroxaban added to ASA is superior to ASA alone in reducingthe risk of major thrombotic vascular events (defined as MI, ischemic stroke, CVdeath, ALI, and major amputation of a…
The objective of this study is to evaluate safety and blood pressure response after renal denervation in patients with uncontrolled hypertension compared to a sham-controlled population, in the absence of antihypertensive medications. These data,…
The objective of this study is to identify whether pelvic collateralisation occurs when a temporary acute obstruction is induced in the left common iliac vein of healthy subjects.
Comparison of the lipid panel between Afinion POCT en routine chemistry analyzer.
To explore the effects of acute fear on the coagulation system while sitting still.
The primary objective of this study is to investigate the safety and feasibility of implanting a WATCHMAN Device in a hybrid setup for AF ablation.
Primary Objective: • Investigate if CT is a reliable modality to detect blood flow distal to the LAAO device validated by TEE.Secondary Objective(s): • Evaluate the reproducibility of position and blood flow measurements: inter and intra observer…
Primary:2. To investigate the prevalence of vulnerable plaques, i.e. plaques with intraplaque hemorrhage on MRI, in individuals with type 2 diabetes, impaired and normal glucose tolerance and a minimal plaque thickness of 2mm on ultrasonography. To…
Primary: To evaluate the effect of AMG 145 on the change in burden of coronary atherosclerosis as measured by percent atheroma volume (assessed with intravascular ultrasound, IVUS) in patients with coronary artery disease requiring angiography for a…