36 results
With a standardized approach in a population with difficult to treat hypertension we want to explore how frequenty PHA is a cause of hypertension and what the test characteristics of the aldosterone-renin ratio are. Additionally we want to…
The purpose of this study is to show that the incidence of new thrombotic events during an additional 6 or 12 months of treatment with rivaroxaban is lower when compared to placebo and that the likely advantage of an extended effect is not offset by…
The main objectives are :Cross-sectional:1. To investigate the extent of atherosclerotic disease of the carotid artery defined as: (a) the intima-media thickness (IMT) (b) the elasticity (c) the degree of stenosis2. To define the degree of…
To visualize occult endoleaks in patients after endovascular abdominal aortic aneurysm repair.
To provide an answer to the following questions: 1. In patients with AD, does treatment with a ChEI improve cerebral hemodynamics? 2. Is there less progression of cerebrovascular lesions on follow-up of AD patients receiving ChEI*s? 3. Does this…
In this trial, current usual care concerning cardiovascular education is described. Second aim is to study what is understood of this education by the patient. Last aim is to study what effect training of GP's on this subject will have on the…
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
The aim of this study is to investigate the safety of treatment of PE in an outpatient setting based on normal pro-BNP levels. The mortality rate and the incidence of hemodynamic instability as well as major bleeding and recurrent VTE in the…
The primary objective is identification of a set of genes as candidate monocyte markers for acute coronary complications and subsequent identification of a prognosis classifier to discriminate vulnerable, stable, and control subjects, based on the…
1. to investigate whether the known chronic inflammatory and hyperoxidative state in patients with severely increased LDL is associated with dysfunctional HDL.2. to investigate whether CVD in FH is associated with dysfunctional HDL.
The purpose of this study is to gain insight into the effects of auditory pacing on the stability and flexibility of hemiplegic gait coordination. It will be examined how auditory pacing can be best administered to improve the quality of hemiplegic…
To assess the influence of bloodpressure, wall thickness, wall properties, and geometry changes throughout the cardiac cycle on the wall stress calculations. Previous analysis were performed with an assumed bloodpressure value, an uniform wall…
To compare the clinical outcome after a first episode of VTE in patients with well-defined thrombophilia who have been identified and treated for a longer duration with anticoagulants with patients with VTE who have not been routinely tested.
1) To determine the prevalence of MetS in the patient population of the MMIJ in IJsselstein aged 20 to 70 years2) To assess the effectiveness of population screening for MetS by general practitioners in a medium-size city in the Netherlands
In this study we will test the study hypothesis whether there is differential gene expression between patients with a history of premature MI and healthy controls when testing RNA obtained from highly purified platelets and monocytes.
Aim of this study is to quantify the relationship between the extent of aortic atherosclerotic disease and neurocognitive dysfunction after cardiac surgery with the use of cardiopulmonary bypass.
The primary objective of this study is to evaluate the impact of carbon dioxide field flooding on the quantitative intraoperative microembolic load of the brain during aortic arch surgery.A secondary objective is to evaluate any concomitant…
The primary objective of this study is to demonstrate the efficacy of the combination therapy of aliskiren (150 mg and 300 mg) and HCTZ 25 mg in hypertensive patients who do not show sufficient blood pressure response to a 4-week treatment of HCTZ…
The aim of the study is to assess the possible additive value of the AGE reader measurement in a group of hospital-controlled (high-risk) persons with type 2 DM.
To determine the best method of measuring venous compliance in women.To determine the influence of orthostatic stress on venous compliance and the best method to measure VC during orthostatic stress.