163 results
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
Dental caries lesions (with ICDAS Codes 3 and 4) can be treated by sealing, offering a less invasive and less costly treatment option with the same results as preparation and restoration of the carious lesions.
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
Patient with isolated resectable colorectal peritoneal metastases (PM) have a 3-year overall survival of 50% after upfront cytoreductive surgery with HIPEC (CRS-HIPEC) alone, and a 3-year overall survival of 65% after perioperative systemic therapy…
The hypothesis is that repeated remote ischaemic postconditioning (by improving vascular, immune and anti-inflammatory pathways) will minimize infarct size and, subsequently, will improve clinical outcome in stroke patients.
We expect that increased oro-sensory exposure and decreased ingestion rate equally and additively increase satiation (lowering intake). In addition, we expect that increased oro-sensory exposure (mastication) increases initial hormone responses of…
Using PlasmaJet Surgical Device during surgery improves the rate of complete cytoreductive surgery in women with advanced ovarian cancer.
We hypothesize that performing a total laparoscopic hysterectomy with same day discharge is safe and leads to equal levels of patient satisfaction when compared to admittance for 1 night.
Men and women do not have the same risk of an ankylosing spondylitis (AS) disease flare during tapering of their TNF blockers. If so, this could probably be associated with differences in body composition.
It is hypothesized that Active+ improves cognitive functioning in elderly with limited mobility through improvements in physical activity. As the literature is inconclusive on characteristics a PA program minimally needs to have in terms of type and…
Mediastinal staging of NSCLC by EBUS/EUS-B with and without additional cervical mediastinoscopy are both effective diagnostic strategies for assessment of mediastinal lymph node metastases. However, omitting mediastinoscopy comprises no extra…
In pregnancies complicated by late PPROM immediate delivery might lead to better long-term outcome.
The primary objective of this study is to evaluate changes in oral health during a 4-month naval mission and once one month thereafter.
Freezing of gait (FOG) is a particularly disturbing and potentially harmful symptom occurring in a majority of people with Parkinson's Disease (PD) over the course of disease. External cues, such as a metronome or bars on the floor, aid in…
Repetitive ePIPAC-OX as a palliative monotherapy is a feasible, safe, tolerable, and potentially effective treatment for isolated unresectable colorectal peritioneal metastases, with low and predictable costs and a low systemic uptake of oxaliplatin…
Providing vascular surgical patients and vascular surgeons with decision support tools will improve the level of shared decision-making during consultation, increase disease-specific knowledge and quality of life and decrease decisional conflict.
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The new interdisciplinary protocol will attract attention to these cases of hand injuries and patients will get a chance of a better coordinated treatment at the early rehabilitation phase. To restore early function of the hand proper instructions…