163 results
The effects of intravenous TRH administration on brown adipose tissue activity in healthy, lean men.
To investigate whether BAT tissue can be activated by intravenous administration of TRH. Secondary objectives are to determine whether intravenous TRH increases the degree of cardiovascular sympathetic stimulation and the response of skin…
The present study has 1 primary and 1 secondary objective:1: The primary objective of the present study is to analyse the effects of supplementation with ITFs of different chain lengths and RSC on hepatitis B vaccination efficacy. The main parameter…
The current study aims to investigate the effects of catecholamine modulation by methylphenidate during initial stages of consolidation on memory retention and the underlying neural correlates of memory retrieval.
The properties of CBD, namely potential effects on variables pertaining to fear extinction and potentially on fear retention/reinstatement while having non of the problematic side-effects found in Δ9-THC, make CBD plausibly preferential over Δ9-THC…
Evaluating the modulatory effects of tACS on frontal brain asymmetry, behavior and mood.
Our primary aims are 1) to test with observational and electrophysiological techniques whether intranasal oxytocin administration to mothers of young infants increases their defensive reactivity and protective approach responses in mildly…
The aim of the study is: to investigate the effect of DCS on the physiological and subjective correlates reflecting conditioned sexual response and subsequent extinction thereof. Hypothesis: We hypothesize that administration of DCS after an…
The study consists of two phases. In the first phase, we aim to investigate whether the dopamine receptor D4 (DRD4) genotype confers differential susceptibility to the effects of early life stress on empathy and prosocial behavior more generally in…
Primary objective is to examine the effect of tryptophan supplementation on the number of accepted unfair offers in the Ultimatum Game. Secondary objectives are to examine the effect of tryptophan supplementation on the response bias in a social…
We aim to assess the neurocognitive mechanisms of tyrosine supplementation in older adults during different forms of cognitive control depending on the prefrontal cortex: working memory, reactive and proactive response inhibition, and effort…
To decrease social conformity by disrupting orbitofrontal cortex by using transcranial direct current stimulation.
To investigate the dynamic relationship between hemodynamic responses to different levels of acute SERT occupancy induced by different doses of the reuptake inhibitor (SSRI) citalopram with 5-HT phMRI, as compared to [123I]FP-CIT SPECT imaging.…
Objective: This study will investigate if AIM can be trained among people with chronic anger management processes. According to the AIM model, repeating avoidance responses to threatening stimuli may reduce aggressive impulses within this population…
The objective of this exploratory study is to investigate the acid neutralisation action of sodium alginate oral suspension versus placebo liquid, within the stomach and to assess suitability and robustness of the pH monitoring methodology.
With the proposed study we aim to gain insight into the effects of oxytocin (OT) on both parents* and grandparents* sensitive, empathic, and protective responses to their (grand)children, and in the neural origins of these responses.The primary…
Primary objective:- To identify the psychological mechanisms via which testosterone modulates value-based decision making, such as testosterone's effects on risk-taking levels, impulsivity and self-control in intertemporal choice, and social…
To record all reactions of healthy volunteers induced by the use of a homeopathic medicine and placebo.
1) To determine whether vaccination with yellow fever results in a higher cytokine response upon restimulation in vitro with non-related infectious pathogens, compared to the response before the vaccination.2) To determine whether BCG vaccination…
The primary study objective is to investigate effects of conditioning on self-reported itch in healthy subjects in response to a short-term validated histamine test. Conditioning effects on other physiological and psychological parameters will be…
The primary objective is to investigate whether exogenous oxytocin administration enhances the placebo effect of positive suggestions as measured by subjective pain intensity and itch ratings in response to validated pain (Cold Pressor Test) and…