591 results
To investigate whether children with OI who use a wheelchair (for long distances) can reliably perform a valid shuttle ride test in order to assess the levels of health-related fitness in this group.
Quantify inflammatory response (through IL-8 production) of bronchial (both commercial available cells and cultivated brushed infant cells) when exposing these to gastric juice from: hospitalized Infants, before and during PPI treatment and age…
Our primary objective is to investigate the development of structural and functional connectivity in autism and ADHD in comparison to the typical development of connectivity. A secondary objective is to investigate the effects of ADHD and autism…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
To compare sex differences in brain functioning using functional magnetic resonance imaging (fMRI) in healthy pre-pubertal boys and girls with a group of children diagnosed with GID. Subjects will have a second fMRI scan, as soon as they enter…
The overall objective of the MOBI-KIDS study is to assess the potential carcinogenic effects of childhood and adolescent exposure to RF and ELF from mobile telephones on the central nervous system (CNS). In order to achieve the overall objective,…
To gain a better insight into the genetic factors that play a role in the etiology of the thoracic aortic aneurysm with the following specific aims:1. Study of specific geneitc factos that play a role in the pathogenesis of both syndromic and non-…
1. What is the complication rate of the initial antibiotic treatment strategy for acute simple appendicitis (radiological proven) in children aged 7-17 years old?
The main objective of this prospective population-based study of patients with proximal SMA in the Netherlands is to register SMA patients in the Netherlands in a socalled SMA-database to study prevalence and severity of SMA types 1-4, to perform…
The overall aim of this project is to elucidate the interaction between stress and epileptic seizures in childhood epilepsy. The specific aim of this study is to compare the possible differences in stress hormone regulation, hippocampal function and…
To investigate the effect of cholic acid supplementation on the clinical and biochemical parameters of Zellweger spectrum disorder
To develop non-invasive markers for tissue changes in skeletal muscle using MR methods
To assess the prevalence, severity and impact of arthropathy in patients with moderate or severe VWD and a history of documented DDAVP or clotting factor concentrate treatment for joint bleeds. To compare arthropathy in these patients to age, FVIII…
To investigate motor connectivity in vivo in patients with SMA using MR- techniques for brain imaging.We will investigate connectivity of upper motor neurons in patients with SMA compared to disease controls (patients with myopathic disorders) and…
To demonstrate differences in neuronal structure and neuronal function in brain regions that control eating behaviour between obese and normal weight adolescents.
Primary Objective: Our main goal is to contribute to the identification of an attentional profile of the paediatric TBI population, by analysing the quality and efficiency of alerting, orienting, executive and sustained attentional functioning. This…
Objective: Our general objective is to investigate the neurobiological substrates of a broader ADHD phenotype.
Objectives and Hypotheses: Objective 1: Social decision making in psychopathic-like adolescents A recent normal population study yielded at least two important findings with regard to social decision making in adolescence. First, when making an…
This study focuses on collecting data on knowledge, attitudes, skills, experiences and needs related to sexuality and relational functioning in high-functioning Dutch boys with autism between 15 and 18 years old (up to and including 17). Data are…
Primary Objective: 1) To study impairment and developmental delay in social cognition (and related cognitive functions) caused by brain damage in patients treated for a brain tumour in childhood as compared to a reference group of chronically ill…