7173 results
The main goal of this study is to validate the VR-game as a tool to provoke OCD symptoms and assess OCD symptom severity. The first objective is to investigate whether the VR-game is able to provoke OCD symptoms in OCD patients. The second objective…
Research questions: Primary questions:* Are the new point-of-care instruments for the measurement of VOCs in exhaled breath feasible for use in children and adolescents aged 6 to 20 years?* Are these techniques able to differentiate between healthy…
Main: To assess the effect of an early extra measles immunization between 6and 12 months of age on the development of humoral and cell-mediatedimmunity against measles following routine MMR immunization at 14months of age.Secundary:Determine effect…
The primary aim of the current proposal is to get a better understanding of how CeD risk genes contribute to disease aetiology. To achieve this, we will apply a holistic approach in which we will study the behaviour of immune cells and the…
The primary objective is to evaluate possible clinical effects correlated with α3β1 and CD151 expression in human epidermal malignancies, and relate these findings to the effects of α3β1 and CD151 deficiencies in skin cancer in the mouse.…
Hypotheses: - For patients undergoing a laparoscopic left or right hemihepatectomy (with or without the need for one additional hepatic wedge resection or metastasectomy), time to functional recovery is reduced by 2 days in comparison with patients…
Primary Objective: To prospectively assess the impact and relevance of several risk factors for SAA/acute wheeze that have been identified in retrospective studies, including our own. Secondary Objective: To assess short-term medical and…
1. To investigate a possible increase intimal-media thickness (IMT) is found of the iliacal artery in endofibrosis2. To investigate a possible altered distention is found of the iliacal artery in endofibrosis3. To compare IMT and distention…
The primary objective is to elucidate whether there is a difference in the outcome of health parameters between IVF children who as an embryo were cultured in two different culture media. As secondary objectives we will investigate how the health…
Various brain areas play a crucial role in both pain and cognition, supporting the existence of a close relationship between pain and cognition. Consequently, it is important to examine whether pain experience changes at the moment the patient shows…
The research objective is to investigate the sensitivity, specificity, and predictive values of the delirium monitor based on 4 standardized EEG electrodes who record brain activity.
The objective of this project is to 1. increase accuracy and reproducibility of the most critical step in hip arthroplasty i.e. cup positioning;2. to alleviate one of the major complications of the straight lateral approach, i.e. abductor…
Explore difference in perforating artery pulsatility index between two patients groups with small vessel disease (history of lacunar infarct and deeply located haemorrhage) and healthy controls.
Primary objective: To compare the cancer detection rate of CEUS targeted biopsies with the cancer detection rate of mpMRI targeted and systematic biopsies. Secondary objective: To characterize the tumors detected by the different biopsy schemes in…
We aim to test the effectiveness of a patient-targeted preparatory tool (*Gesprekswijzer*) and an oncologist-targeted communication skills training to enhance shared decision making in consultations about palliative systemic treatment. The primary…
Primary objectiveTo assess the outcome of NOAC associated bleeds and emergency invasive surgery or procedures. Secondary objectives1) To describe the treatment of patients presenting with NOAC associated bleeding2) To evaluate the current…
The aim of this study is to identify Galectin-1 and -3 as possible biomarkers in capsular contracture. Moreover, we plan to investigate whether HLA-typing and IgE levels in subjects can be used to predict the chance of development of capsular…
Primary Objective: to study the differences in CD4+ T cell subsets (Th1/Th2/Th17/Tregulatory/Tsenescent) between GCA patients and healthy controls at diagnosis and during follow up and in remission. Secondary Objective(s): - To characterize the cell…
We will investigate the relationship between this permeability measure and (i) cognitive performance and (ii) the status of MRI visible cerebrovascular pathology (i.e. white matter hyperintensities, lacunar infarctions, microbleeds) in the most…
The aim of Prevent CardioKids is to evaluate to what extend disturbed vascular function markers are present in children of different weight categories and whether these are age dependent. Also differences * and relationships between * vascular…