158 results
To identify host risk factors through genetic and immunological screening that may be associated with the development of cardiac SAEs following CHMI. Identification of such factors may on the one hand allow at-risk individuals to be screened out…
By means of this study we want to find out whether there are certain characteristics that can influence or predict the course of Crohn's disease. We want to do this by collecting data on diet, inflammation levels in the blood, complaints and…
Objective: The primary objective of this study is to investigate interoceptive abilities in adolescents with AN. To capture the multidimensional perspective, interoceptive abilities will be studied on an accuracy, sensibility and awareness level.…
Primary Objective:Delineate the differences in cellular composition and function at the maternal-fetal interface in patients with SLE compared to healthy women Secondary Objectives:- Establish a novel in-vitro model to study cell-cell interaction at…
The main study objective is to examine the effect of the PTWD program on glycaemic control of lower-educated participants with T2D. The secondary objectives include the effect on medication use, use of care and T2D self-management behaviours. We…
The study*s main objective is to measure blood micro- and macronutrient and amino acid levels in adults with PKU on a protein substitute and compare with age- and sex-matched non-PKU comparison subjects.
Beyond mapping the pregnancy-related neural plasticity in structure and function, this project is designed to reveal functional and behavioral implications of the transformations impacting a woman*s brain across this major transitional stage. The…
The main objectives of this study is to analyze differences in the gut and vaginal microbiome between healthy and PCOS women and investigate whether these differences correlate with PCOS characteristics. In addition, we want to look at a possible…
The objectives of this are to establish the safety, tolerability, and preliminary efficacy of VRDN-001, and the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of VRDN-001 in NHV and TED patients over a dose range of 3.0 to 20.0 mg/kg.
The aim of the study is to determine whether children who have been admitted to the ICU for an RSV infection in their first year of life and now are at school age:1. have more respiratory complaints than controls (based on a short questionnaire…
The primary objective of this study is to establish whether cerebellar patient populations can adapt and learn to maintain standing balance when sensory-motor relationships of balance are modified. By comparing patient behavior with age-matched…
1. To study the possibility to detect gynaecological malignancies in Pap smears and blood of women with gynaecological cancer, using MeD-seq and biomarker assays, in order to develop new reliable screening methods for all different gynaecological…
The primary study objective is to compare the clinical outcomes of patients treated with the FlowTriever System versus Catheter-Directed Thrombolysis (CDT) for use in the treatment of acute intermediate-high-risk pulmonary embolism (PE).
The primary objective of the current study is to assess the feasibility of ROBERT® -SAS training in clinical setting, in acute stroke patients, including patient and therapist perspectives
The first aim of this study is to use an in vitro approach using patient*s derived material to accurately and rapidly predict the optimal therapeutic approach that will predict a good clinical response in individual patients. The second aim of this…
The primary objective of this study is to determine the variation in postprandial glucose responses to the same meals/food products and how this relates to the variation in postprandial glucose responses over a 9-week fully controlled dietary…
Primary objective: To investigate baseline* left ventricle longitudinal strain rate values in a population of growth restricted fetuses and to compare these with a population of appropriate for gestational age fetuses.Secondary objective: To…
To investigate the effects of ICIs (anti-CTLA4, anti-PD1, combination anti-CTLA4/PD1) on vascular inflammation (PET-CT) in stage III melanoma patients. We hypothesize that the increase in vascular inflammation will be greater in the exposure group…
The main objective of this study is to validate a simple screening tool and a best-practice assessment battery for the different components of HRPF against gold standard measures. Secondary objectives are to objectively assess the incidence of…
Primary Objective:The primary objective of this study is:• To evaluate the efficacy of namilumab in subjects with chronic pulmonary sarcoidosis (CPS).Key Secondary Objective:• To evaluate the effect of namilumab on proportion of subjects on OCS…