1621 results
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
Identification of the proteins that are involved in neurite outgrowth in PDR. We want to determine what protein levels are increased in the vitreous by local production and which RNA transcripts are present in the fibrotic membranes of patients with…
To assess microglial activation in first episode patients with psychotic symptoms and first episode medication naïve patients with psychotic symptoms compared to healthy controls using the positron emission tomography (PET) tracer [11C]-R-PK11195.
Primary Objective: What are the consequences of irradiation for the human jaw bone and oral mucosa on a macroscopic, microscopic and molecular level?Can possible prognostic factors be identified for the occurrence of peri-implantitis, dental implant…
The principal aim of this project is to identify genetic biomarkers involved in susceptibility for drug-induced liver injury in a set of candidate genes (genes relevant to metabolism of drugs and immune system genes).The results of this study will…
The main goal of this study is to recruit and obtain magnetic resonance images in a large sample of bipolar patients and controls from the Netherlands, in order to find brain abnormalities specific for bipolar disorder. We will also perform genetic…
The main aim of the present study is to improve our understanding of the role of blood-brain barrier function and cerebral perfusion in dementia of the Alzheimer*s type.
Quantify inflammatory response (through IL-8 production) of bronchial (both commercial available cells and cultivated brushed infant cells) when exposing these to gastric juice from: hospitalized Infants, before and during PPI treatment and age…
Objectives: 1. To investigate the types of antitrombin deficiency in these families2. To find the mutations in our families/patients with antitrombin deficiency.3. To establish the risk of VTE due to these mutations and subtypes.(comparing…
Our primary objective is to investigate the development of structural and functional connectivity in autism and ADHD in comparison to the typical development of connectivity. A secondary objective is to investigate the effects of ADHD and autism…
Primary Objective: To study changes of T cell subsets (Th1/Tc1, Th2/Tc2, Th17/Tc17, regulatory T cells and senescent T cells) in healthy ageing and unhealthy ageing. Secondary Objective(s): - To study the immune risk phenotype in healthy persons…
If normal doubt occurs, will OCD patients differ from non-OCD anxiety patients and healthy controls in how much uncertainty they will experience and will OCD patients respond to this with more perseveration (chekcing behavior) than non-OCD anxiety…
1. Are there differences between patients and controls in circadian movement rhythmicity and sleep duration?2. Are these objective measures associated with subjective sleep complaints?3. Are these objective measures associated with decreased quality…
To get more insight into lymphocyte kinetics during immune reconstitution after hematopoietic stem cell transplantation
This project aims to understand the symptomatology PD in the light of functional brain interactions, in the hope of elucidating the role of the frontal striatal system to behaviour.
The purpose of this study is to make it possible to make a prediction of risk of amputation stump wound healing without the need for re-intervention and whether a secondary amputation.
The main aim is to validate the hypothesis by Sampson on retrograde menstruation by using modern imaging modalities. •to evaluate if the amount of blood-stained peritoneal fluid measured by TVUS and MRI during menses is greater in women with…
To study the differences in adipose tissue, liver and circulating levels of RBP4 in lean versus obese, diabetic and obese insulin, non-diabetic subjects in relation to glucose fluxes and hepatic triglyceride content
To compare sex differences in brain functioning using functional magnetic resonance imaging (fMRI) in healthy pre-pubertal boys and girls with a group of children diagnosed with GID. Subjects will have a second fMRI scan, as soon as they enter…
To determine the frequency of MBL and FCN SNPs in patients with a history of a proven gram-positive bacteremia, compared to patients without such history. A secondary objective is to determine whether extracorporeal circuits, used in cardiothoracic…