155 results
This study will answer the question if (repeated) abdominal amnioninfusion after midtrimester PPROM with associated oligohydramnios improves perinatal survival and prevents pulmonary hypoplasia and other neonatal morbidities. Moreover, it will…
Primary ObjectiveDifference in incidence of an avulsion injury and morphological changes of the levator ani muscle after a first normal vaginal delivery between participants with and without a mediolateral episiotomy.Secondary ObjectiveChanges in…
Is recurrent miscarriage an independent risk factor for an increased cardiovascular risk?
Main objective of this pilot study is to investigate the placental bed histological phenotype and evaluate a scoring system for lesion characteristics of the placental bed spiral artery in pre-eclampsia and uncomplicated pregnancy. The secondary…
The primary objective of this study is to evaluate neurophysiologic changes of the pain centres of the brain (the differences in particular in the thalamus, primary and secondary somatosensory cortex, insula, anterior cingulate cortex and the motor…
The main goal of this study is to establish the reliability (internal consistency and interrater reliability) and validity (discriminant, contruct and predictive validity) of the INCAS. Differences between the SMI and healthy group will be studied (…
The primary objective is to determine if there is an association between the presence of vertebral and/or rib anomalies and congenital malformations, aneuploidy or adverse fetal outcome, in order to assess whether detailed evaluation of the…
Aim of the study is to get informed on the outcome of women treated in the MUMC for obstetric anal sphincter injury between 2005 and 2012. The controlgroup is matched for maternal age at delivery, parity, mode of delivery and child weigth.
To evaluate the effect of CP in the Dutch setting on psychosocial- and health outcomes (concerning the pregnancy) and the success of implementation of CP (including a costanalysis)
To answer the following questionsDo RA-specific autoantibodies cross the placenta, and can they be found in fetal cord blood in the offspring of mothers suffering from RA?Do RA-specific autoantibodies in fetal cord blood display different…
We aim to determine an association between the presence of complement binding anti-paternal HLA-C antibodies and preeclampsia.
Primary objectives:• To demonstrate that low ratios of sFlt-1/PlGF predict absence of PE / eclampsia / HELLP (according to diagnostic criteria) within one week after start visit (= Visit 1).• To demonstrate that high ratios of sFlt-1/PlGF predict PE…
Disease activity, perianal involvement and lesion localisation are important influential parameters making sure no pregnancy is exactly alike and mode of delivery needs to be considered on an individual patient level.A complete anorectal function…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
Does HLA sharing in couples with recurrent miscarriage play a role in recurrent miscarriage of unknown etiology?
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery.
Primary Objective: The main objective of this study is to analyse the effects of pregnancy on levels and percentages of CD8 cell subsets in peripheral blood both during and after pregnancy.
Primary Objective: To determine the accumulation of AGEs in the skin and serum of pregnant women with DM1, DM2 or GDM, in comparison to healthy pregnant women and non-pregnant women with DM1 or DM2 and to determine the accumulation of AGEs in the…
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
The overall aim of the study: To assess whether an exercise program can improve insulin sensitivity and fasting plasma glucose levels of women at high risk for gestational diabetes, assuming that this will normalise their risk of gestational…