123 results
To investigate causes and predictors for primary or secondary allergy profiles for soymilk
Primary Objective: To define a top set of genes that most reliably (r >=0.95) distinguish psoriasis from normal skin. We will define this set from differential methylation genes to indicate potential biomarkers.Secondary Objective(s):…
To describe the composition of the BMZ along the interfollicular and follicular epidermis of perilesional HS skin and to investigate whether the expression of these proteins differs from normal skin of healthy control patients. Additionally, a…
To test the suitability of OCT for in vivo imaging of the vascularisation and surrounding tissue of burn wounds and scars.
The aim is to validate the hypothesis that a positive history defined as dermatitis at exposure to a scented product and thereafter avoidance of such products in fragrance-hypersensitive individuals and a positive patch test result to fragrances is…
To perform a comprehensive analysis of the cellular infiltrate in lesional AD skin, using state of the art immunohistochemical techniques.
Primary objectivesTo study the relation between the physiological, microbiological and immunological status of the skin and the response to an external stimulus; to assess:• the relations between microbiome and/or immunology and the skin type;• the…
The study will be designed as a multicenter study to evaluate the impact of several parameters influencing the sensitivity and specificity of skin self tests.The parameters are:- Product applied: hair colouring formula mixed with developer (in use…
Aim of this study is to explore the relation between Th1-cell mediated diseases as psoriasis/psoriatic arthritis and Th2-cell mediated asthma, allergic rhinoconjunctivitis, atopic dermatitis and hand eczema. Question is whether a dysbalans in…
Primary objectives:• To explore whether daily oral treatment with 30 mg prednisolone modulates biomarkers for adverse metabolic effects in a similar manner in patients with chronic atopic dermatitis as compared to healthy volunteers.• To determine…
To investigate the effect of a sunscreen, a topical antioxidant and a topical corticosteroid on erythema, infiltrating neutrophils and oxidative stress following exposure of the skin to SSR.
The major aim is to apply deep sequencing technology to obtain a detailed unbiased overview of the bacterial microbiome of human skin. This will be performed in healthy individuals, psoriasis patients and atopic dermatitis patients. Furthermore, we…
This single-center investigation will assess the prevalence of psoriasis in a population of patients with hepatitis C and compare the prevalence in those patients receiving pegylated interferon-* therapy to those not receiving pegylated interferon…
The aim of this study is to detect the hitherto unknown factors which possibly can explain the difference in acetylation. Therefore we need to collect blood from PPD allergic patients and healthy volunteers, to determine not only the genotype, but…
Within the observational study WP9, there will be 3 substudies. First the microbiological aetiology of LRTI will be studied by comparing test results in 3000 healthy controls to findings in 3000 adults with LRTI. Bacterial resistance rates will be…
To evaluate the agreement between the results of four diagnostic tests for metal allergy (in vivo patch tests, resp. Lymfocyte Proliferation Test (LPT), a modified LPT (MELISA®), and the Lymfocyte Cytokine Production Test (LCPT), and the clinical…
The primary aim is to study the effect of treatment of severe AD patients with Myfortic on DNA-repair after irradiation with UVB.A secondary aim is to study the effect of treatment of severe AD patients on atopic status, measured as total IgE and…
In this project we would like to find out whether Sellotape stripped healthy skin can be used as an in vivo model for mechanical skin damage. This would contribute to more knowledge about growth, differentiation, inflammation and mechanical…
The overall aim of the study is to investigate the Ponto wide implant considering; initial implant stability, stability over time, skin reaction and long term success when loaded at 3 weeks post surgery. Patients* quality of life improvements…
The objective of this study is to analyse the microbiome of the skin of patients with ichthyosis vulgaris (FLG -/-). This microbiome will be compared to the microbiome of healthy volunteers (FLG +/+) and first grade family members of patients with…