689 results
The proposed study aims to develop a prediction rule for response to biological treatment in RA (i.e. effectiveness and adverse events). Guidelines for treating the disease with biologicals using the (derived) prediction rules will be defined. To…
The assessment of the duration of the cellular immunity to Bordetella pertussis after an extra ACV booster and the relationship between the memory B- cells and antibody responses. The methods used in the study are:B- and T- cell memory responses and…
This project aims to understand the symptomatology PD in the light of functional brain interactions, in the hope of elucidating the role of the frontal striatal system to behaviour.
In humans with SCI, we propose to use functional magnetic resonance imaging (fMRI) to: 1) examine the cortical areas that are activated during voluntary contractions, and 2) evaluate how cortical activation patterns change as a muscle is fatigued.…
The main objective of the current study is to search for biomarkers, which will be investigated with their predictive value with respect to the course of COPD in lungfunction, exacerbations, health care use and mortality. The effects of the…
A. Determine the placement of the Maple-probe in relation to the anatomy of the pelvic floor musculature.B. Determine the normal rest tone of the pelvic floor musculatureC. Determine the normal activity of the pelvic floor musculatureD. Determine…
To determine the incidence of hypopituitarism in patients after SAHTo identify neurological parameters that predict hypopituitarism after SAHTo determine the value of a Ghrelin test shortly after SAH, to identify subjects with GHD.To determine the…
The current study seeks to explore the SDOCT potential in a large group of patients in a clinical setting, and to compare it to existing, standard techniques.
This study will investigate the relationship between autonomic nervous system function and pain in fibromyalgia, with a specific emphasis on awareness of bodily sensations, also refered to as interoceptive awareness, as a potential modulator of pain…
The current study is designed to test the hypothesis that the medulla in transplanted kidneys is still hypoxic at 1 day after transplantation using a non-invasive method: BOLD MRI.By studying two groups a comparison can be made between patients…
Identify and further explore the structural brain alterations in ALS patients in comparison to healthy controls and to investigate the correlations of anatomical changes with clinical variables.
This study aims to investigate differences in spatiotemporal properties of the active movements in of the cervical spine in the sagittal plane in chronic WAD patients and healthy controls.
1. Is there a difference between the level of activities and participation among adolescents with chronic musculoskeletal pain as compared with the activity and participation level of adolescents not suffering from chronic pain?2. What is the impact…
Discrimination of probable AD patients from healthy volunteers by ZK 6032924 PET imaging as evaluated by visual analysis of the brain distribution patterns and by SUV values in probable AD patients as compared to healthy volunteers for brain imaging…
The aim of the proposed research is to test, by the use of functional magnetic resonance imaging, the hypothesis that psychometric schizotypy (referring to, e.g., subclinical hallucinations in healthy people) is associated with reduced activation of…
With this project we aim to clarify the differences in airway pathophysiology between asthmatics and healthy controls that underlie the prolonged survival of virus and the exaggerated inflammation in virus-induced exacerbations of asthma. We will…
To investigate the relation between a known genetic variation in a set of selected genes involved in the recognition of microorganisms and inflammation and the frequency of respiratory tract infections in a group of children with DS.
In the current study this hypothesis will be tested by examining whether blood serotonin levels, which are indicative of central serotonin levels, differ between infatuated and non-infatuated individuals. Furthermore, it will be investigated whether…
The main goal of our proposal is to study the interaction between cognitive and emotional capacities in schizophrenia. In numerous studies patients with schizophrenia show impairments in all major cognitive domains (6) as well as impairments in the…
To characterise the number, phenotype and functionality of regulatory T cells and cytokines produced in the peripheral blood of children diagnosed with asthma.