2029 results
MRD detection using next generation sequencing (NGS) on circulating tumor DNA (ctDNA) from PTLD patients using a gene panel previously used in diffuse large B-cell lymphoma (DLBCL) may be feasable
Reinforcement with prophylactic slowly-resorbable TIGR Matrix mesh in high-risk patients undergoing midline laparotomy is effective.
1. It is feasible to perform lymphatic mapping in locally advanced uterine cervical cancer. 2. There are lymph nodes on the lymphatic map which are not included in the radiation treatment plan or did not receive sufficient radiation dose.
The aim of this study is to evaluate the efficacy of HH-RCM in the presurgical margin delineation for LM treated by conventional surgical excision.
The hypothesis: the overall survival of AML patients is influenced by AML type, age, genetic aberrancies, comorbidity and performance status of the patient as well as type of treatment.
The hypothesis to be tested is that treatment with three courses of R-DHAP + MTX combined with rituximab i.t., followed by ASCT is feasible and that the efficacy meets the expectations as described in the protocol.
Reproducibility and validity of the new Hemodynamic Cardiac Profiler (HCP) device in rest and exercise in healthy volunteers will be ICC > 0.60.
1) Left bundle branch area pacing is superior over right ventricular (RV) pacing. 2) Acute electrical and hem-dynamic effect is comparable between LV septal pacing and left bundle branch pacing.
We hypothesize that the supplementation of omega-3 polyunsaturated fatty acids will improve comorbid depression, anxiety, and cognitive functioning in patients with anorexia nervosa, subsequently improving treatment outcomes.
I. Daily adaptive IMPT for locally advanced cervical cancer is clinically feasible and will be able to spare the organs at risk to a significantly greater extent than photon-based IMRT/VMAT, while maintaining coverage of the target volume. II. There…
We hypothesize that higher levels of pro-inflammatory macrophages in pregnancy are related to early placental developmental defects (i.e. decreased trophoblast invasion and SA development) or inflammation and oxidative stress later in gestation,…
1) After the initiation of targeted CFTR therapy: a. Microbiome diversity increases (primary hypothesis, also used for sample size calculation) b. Well-adapted microbial species (e.g. Pseudomonas, Achromobacter) decrease in abundance c. The…
1. Targeted LV-lead delivery is safe and feasible in a multicenter setting. 2. Image-registration using 2D fluroscopy is non-inferior compared to standard 3D image registration (validation in first five patients). 3. Targeted LV-lead delivery will…
It is assumed that treatment with Imatinib mesylate will inhibit fibroblast proliferation in systemic sclerosis thereby leading to an improvement in clinical condition in patients.
Self monitoring of the ECG by the patient contributes to the correct diagnosis, reduces the frequency of cardiology consultations and leads to less side effects and lower dosage of medication. Patients become more confident and gain more insight…
Due to surgery and radiotherapy lymph drainage pathways in recurrent breast cancer could be altered. These aberrant drainage pathways could be detected with lymphatic mapping and sentinel node biopsy leading to a more thorough staging and possible…
To explore the amount of straylight in patients implanted with a Clareon monofocal IOL in one eye and a Vivinex XY1 monofocal IOL in the other eye and compare these straylight values to those in the normal pseudophakic eye (i.e., the pseudophakic…
Refinement of the CHIP prediction rule will lead to a more efficient use of head CT in patients with minor head injury
Ouderen met Gedragsmatige en Psychologische Symptomen van Dementie in de Geestelijke Gezondheidszorg
the hypothesis of this study was that CGM would be applicable to the treatment of challenging behavior in patients with BPSD and CMPT