48 results
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…
An intervention with a fortified drink containing iron, zinc, vitamin A, vitamin C, folate, vitamin B-12 and B-6 and/or omega-3 polyunsaturated fatty acids over one year can improve cognitive performance in Australian well-nourished children and…
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
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Since several years, anti-VEGF agents have become available for the treatment of neovascular age-related macular degeneration (AMD) and have substantially improved visual prognosis in patients suffering from this condition. The anti-VEGF agent used…
We believe that a routine graft biopsy at 6 and 12 months together with graft function represents the best surrogate marker for late graft loss.
The goal of this study is to determine whether radiosensitization with carboplatin or the addition of Isotretinoin to maintenance therapy improves cure rates for children with other than average risk medulloblastoma/PNET.
We hypothesize that by combining the recently validated gout flare criteria with a patient-friendly app and real-time monitoring, we can implement a gout flare measure that is less prone to recall bias and can be used by patients at home. It could…
We hypothesise that CAP is a safe treatment that reduces bacterial load on the wound surface and promotes wound healing.
The goal of this study is: 1. To offer a uniform, standardized concept for the treatment of children and adolescents affected by low grade glioma; 2. To improve progression free survival following non-surgical therapy for children without NFI with…
To assess the change in arterial wall inflammation, measured with 18F-FDG PET/CT, in patients with increased CV-risk and statin intolerance due to statin-associated muscle symptoms after PCSK9 inhibition
A SPT has been proposed to screen subjects with increased risk of hypersensitivity reaction to Ruconest. Subjects with RA and subjects with clinical CMA have an increased risk of hypersensitivity: although cow's milk proteins differ from rabbit…
Specific areas of language production are affected in children and adolescents with classic galactosemia, in particular syntactic production. Further, it is hypothesized that the galactosmic patients will show a profile of general cognitive…
Opening wedge HTO treated with DBM will better match one year post-operative mechanical axis alignement with pre-operative planned correction then opening wedeg HTO filled with autogenous iliac crest bone.
Comparison of two new techniques for detection of small bowel pathology: MR enteroclysis and videocapsule enteroscopy with double-balloon enteroscopy with respect to diagnostic yield, accuracy of findings, and patient preference.
For patients with breast cancer who are not applicable for breast-saving treatment (because of tumor characteristics), who prefer an amputation or who undergo a prophylactic amputation an immediate breast reconstruction is a standard offer. A…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
Maintenance thalidomide delays the time to progression with 50% in patients who do not progress after > 3 cycles of pemetrexed containing chemotherapy.
NAVA (neurally adjusted ventilatory assist) is a newform of artificial respiration, based on the electrical activity of the diafragma. We want to investigate wether there are fysiological differences between the conventional mode and NAVA.