327 resultaten
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
1. Prosthetic valve characteristics (type; location; size resulting in the presence/absence of PPM) are related to functional outcome and quality of life; 2. The incidence/spectrum of prosthetic valve-related complications in adults with CHD differs…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
The aim of this protocol is twofold. 1. Firstly, we aim to combine the new response monitoring method (PET imaging) with the present technique (dynamic CE-MRI imaging) in order to discriminate between favourable and unfavourable response of the…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
An activity stimulation program improves mobility performance and fitness in children with cerebral palsy.
This study was therefore designed to determine whether cinnamon lower postprandial blood glucose, and insulin levels in subjects with type 2 diabetes or impaired glucose tolerance.
Early treatment of a clinical varicocele in subfertile men results in more spontaneaous pregnancies as compared to no treatment.
By detection of disease specific deviations in emotion processing in unipolar vs bipolar patients, affective neuropsychological tests and fMRI could be used to discriminate between both affective disorders.
Use of the Online Exercise Coach, an online tailored exercise program, will enhance compliance with a prescribed exercise program.
We expect a decrease in the expected satiating capacity of the test food after repeated exposure to the low-energy-dense version of the soup and an increase in expected satiation after the repeated consumption of the high-energy-dense soup.
In the elderly patient with a proximal intracapsular femoral fracture a hydroxy-apatite coated uncemented hemi-arthroplasty will lead to a lower mortality rate and less servere complications compared to a cemented hemi-arthroplasty.
Does suppletion of vitamine D3 (cholecalciferol) have an effect on the systolic blood pressure in hypertensive, vitamin D insufficient patients? 1. H0 hypothesis: there is no effect on the systolic blood pressure; 2. H1 hypothesis: the systolic…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
Een klinisch behandelprogramma met een opnameduur van acht weken gevolgd door een intensief vervolgprogramma voor kinderen (8-19 jr.) met ernstige obesitas is kosten effectiever dan een klinische interventie met een opnameduur van zes maanden en…
Our hypothesis is that routine application of elastic stockings after varicose vein surgery is not beneficial with regard to pain- and physical functioning scores, complications, edema formation, time before returning to work and analgesics…
It is hypothesized that aerobic exercise therapy (AET) and cognitive behavioural therapy (CBT) are both effective in improving activities and QoL in patients with Amyotrophic Lateral Sclerosis (ALS) compared to the usual care.