17905 resultaten
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
A higher percentage of patients with MRD levels <0.1% (MRD negativity) after up to 2 courses of induction chemotherapy plus quizartinib, as measured in the bone marrow using MFCM before start of consolidation therapy, compared to a historical…
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
Prevention of the progression of TMD to ML-DS by chemotherapeutical profylaxis can be possible.
The use of videoglasses will lead to more anxiety reduction than hearing preferred audio in patients undergoing surgical procedures under local anesthesia.
By measuring biomedical variables, such as movement, temperature, heart rate variability, blood volume pulse and skin conductance, by means of a wearable (wristband), stress-related parameters can be measured easily and continuously. It is…
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. Eventually, inadequate tissue oxygenation will lead to pathological alterations, especially at the…
Study the effects of short-term cognitive behavioral therapy (CBT) given by psychiatric nurse practitioners with familiar patients with chronic benzodiazepine use and new patients in the family practice with sleepingdisorders.
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
Since progression from NAFLD to NASH is associated with significantly increased risk of morbidity and mortality, there is a clinical imperative to identify the NAFLD patients that rapidly progress to NASH from those who will remain in the NAFLD…
Teres Major muscle transfer group will show significant better improvement in active abduction and external rotation than the LD group after 1 year.
Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
The aim of this study is to investigate the immune response to the tetravalent MenACWY-TT vaccine administered as a second meningococcal vaccination and compare the booster response to MenC with the booster response to the monovalent MenC-TT…
DBS-related cognitive decline and psychiatric side-effects in Parkinson's disease (PD) patients can be studied from a functional- and structural network point of view. We will characterize functional and structural brain networks in PD patients…
This study aims to underpin the delivery of longstanding exercise therapy in the subgroup of patients with RA and complex disability. There are 3 research questions to be addressed: 1. Is longstanding, optimized active exercise therapy more…
Does sildenafil improve tumour perfusion?
Victims of rape report significantly less PTSD symptoms at 4-,8- and 12-weeks follow up, after two sessions of Early EMDR therapy compared to TAU.