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We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
Our hypothesis is that adolescents that have been educated on an 'enjoy being fit' elementary school exhibit healthier scores than adolescents that have been educated on a regular Elementary school on the set of outcome variables. However…
Patients with ADAM12 > 203 ng/mL in their serum benefit from the addition of biweekly tocilizumab for 3 doses to neoadjuvant chemoradiation before esophagectomy
We anticipate that students who will receive the Internet-based intervention based on their symptoms will have high satisfaction and show high adherence to the program. We also expect to find significant improvements in symptoms of stress /mood and…
We expect an increased bone mineral density in the calcar region compared to the other ROI’s. Furthermore, we expect early detection of decreased mineral density of the femoral head in patients developing osteonecrosis of the femoral head.
We hypothesize that providing feedback to hospitals will reduce practice variation
Drug-induced Sleep Endoscopy with cocomittant jaw thrust maneuver is a suitable predictor for succes of oral appliance treatment.
The aim of this study is to investigate the non-inferiority of perioperative continuation of aspirin patients undergoing spinal surgery, compared with the current policy of perioperative discontinuation of aspirin.
We hypothesize that use of the shortened MRI protocol instead of ultrasound in the postoperative surveillance will reduce the risk of and extend the time to possible recurrent liver metastasis.
1. Women who receive early intervention EMDR will have less PTSD (symptoms) than those allocated in the care-as-usual group. 2. Early intervention EMDR will have a positive effect on Quality of Life, Fear of Childbirth, depressive symptoms, mother-…
Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma
We hypothesize that the number of patients without vertigo spells at 12 months follow up will be higher in the group that has undergone EDB than in the decompression group.
The objective of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of ALKS 6610 after single ascending oral doses in healthy adult subjects.
Good Inter-observer agreement for important markers such as bowel wall thickness and Doppler activity
We hypothesize that the pregnant women in the intervention group (using the PRFS ) will be more satisfied about the perceived quality of antenatal care than the women in the control group.
SU results in a higher rate of self-initiated toileting and a decrease in urinary/faecal accidents.
TAM and ven can be used with acceptable safety and there will be a measurable overall respons. Study is exploratory, so no numbers are given yet.
We hypothesize that compared to traditional in-OR surgical intervention, in-office, needle arthroscopic meniscopexy will be preferred by patients, decrease time-to-recovery and be less costly.
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
-To compare the diagnostic accuracy of LUS with low-dose CT for the detection of pneumonia in COVID-19patients and in triaging those patients.