2334 resultaten
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
We hypothesize that socioeconomic inequalities in diet quality are partly explained by differential dietary costs.
As plasma glucose during surgery increases, because of the surgical stress response and accompanied insulin resistance, this will lead to an acute supply-demand mismatch and excess of glucose in the brain. We hypothesize that this leads to…
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
By giving high dose, radical, radiotherapy to patients with recurrent lung cancer, the overall survival can be prolonged and local control rate can be increased which can be done with acceptable toxicity for the irradiated normal tissues.
The use of structural biomarkers (e.g. fundus autofluorescence imaging, optical coherence tomography or a combination thereof) may show a much more gradual progression that is indicative of functional vision loss at a later stage.
It is hypothesized that this personally tailored physical activity program (I’M FINE intervention) will be more effective in improving physical fitness and enhance daily activity in individuals with slowly progressive neuromuscular diseases (NMD)…
A structured use of clincal features in combination with bloodtests applicable as point-of-care(POC) tests, can improve recognition and outcome in sepsis patients
Difference in phenotype between nonbullous and bullous pemphigoid can be explained by gene expression and/or eosinophillic activity in the skin.
Physicians will speak of an 'asthma cough' and while coughing is one of the symptoms of asthma, the specificity of coughing as a predictor for asthma is known to be low. It is hypothesized that the coughs and it's derived parameters,…
We hypothesise that the relations of total fat and fatty acid (FA) subtypes (SFA, MUFA, or PUFA) with CHD are modified by their food source. We aim to directly compare relations of FA subtype intake from dairy and meat with risk of CHD by using…
Edible insects contain iron at similar concentrations as meat and is mostly organically bound. It is currently not known to what extent iron from edible insects is absorbed in humans.
We hypothesize that by combining the recently validated gout flare criteria with a patient-friendly app and real-time monitoring, we can implement a gout flare measure that is less prone to recall bias and can be used by patients at home. It could…
Impairment of immune-complex-induced neutrophil activation caused by PDE4 inhibition, making it a potential target for the treatment of pemphigoid diseases.
Primary hypothesis is that MRDTI will demonstrate acceptable sensitivity and specificity for the diagnosis of acute SVT and the differentiation between acute and chronic SVT.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status.
THypothesis: The integration of measurement outcomes in response to the PhenFlex challenge test will enlarge small, single differences by combining multiple but small effects on metabolism leading eventually to a measurable health difference before…