23 resultaten
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
We hypothesize that performing a total laparoscopic hysterectomy with same day discharge is safe and leads to equal levels of patient satisfaction when compared to admittance for 1 night.
There are factors that restrict and promote exercise behavior in children with asthma. An new developed exercise game including tools to overcome these factors will be stimulating in physical activity and can stimulate exercise behavior.
The aim of this study is to develop and validate an age-specific checklist that can help clinicians to identify elderly patients with personality disorders in need of highly specialized mental health care.
E-PsEYE in comparison with usual care is cost-effective.
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
1. We first propose that in advanced TC, not only tumor-associated macrophages (TAMs), but also circulating monocytes and bone marrow (BM) myeloid progenitors are functionally reprogrammed by tumor-derived metabolites even before their recruitment…
Patients who received CBM-I training will start their exposure therapy with lower anxiety levels, and their anxiety levels will reduce faster compared to patients that receive a placebo training.
This is an exploratory study to further delineate the microenvironment of the PT and (S)LNs in cervical cancer.
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
Work package A The aim of work package A is to examine the effectiveness of analogy learning (based on implicit motor learning principles) compared to explicit motor learning on walking performance in people after stroke. Work package B The primary…
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…
Intraoperative verification of paranasal sinus malignancy resection with cone-beam computed tomography will lead to a higher rate of radical resection
Breast cancer is the most common type of female cancer worldwide. Early detection has proven to have a positive influence on the prognosis and survival rate. An important aid in the detection and diagnosis of breast cancer is the use of medical…
The objective of the study is to investigate the feasibility of a tailored physical therapy program for metastatic breast cancer patients.
The reported incidence of delirium in the intensive care unit varies from 16 to 89%. A delirium is associated with increased mortality, increased hospital length of stay, higher cost of care and cognitive impairment. The Pain, Agitation and Delirium…
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
The hypothesis is that this load-reducing orthosis will result in reduction of symptoms and regeneration of cartilage in an osteoarthritic knee joint.
Cabozantinib improves overall survival in patients with hepatocellular carcinoma compared with placebo
Breast-conserving surgery followed by radiotherapy is a safe and effective procedure to treat early stage breast cancer. In many women, this type of treatment gives beside a good survival a good cosmetic result. However, some women will be troubled…