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It is increasingly recognized that the immune system is a major player in this obesity related disease and the switch from benign to malign (insulin resistance and DM2) obesity is associated with changes in the immune system . In this regard, animal…
Currently, a major issue in fetuses with FGR is the diagnostic process. Children born below a certain population based centile are either constitutionally small or growth restricted. Children grown above that centile may be growth restricted…
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Treatment of a subcapital metacarpal fifth fracture with a compression bandage gives the same functional outcome a treatment with paris plaster
The hypothesis of this study was that the Oxord UKA will not hamper the accuracy of the CT-based PSG for TKA during revision surgery to restore biomechanical limb alignment and prosthetic component positioning as calculated by the software and the…
Short-term (1-year) results of renal transplantation are now excellent (over 95%). Long-term (10-year and longer) results are, however, still disappointing. Where most research has focused on immunosuppression and infections, we hypothesize that due…
Deep neuromuscular block has advantages over a moderate neuromuscular block in term of outcome (pain, respiration) but has otherwise no effects on the patient
Acute stress and increased levels of dopamine in the brain will lead to a shift from goal-directed behaviour to habitual behaviour. The shift will coincide with a change in functional connectivity between brain areas governing goal-direct and…
Magnetic Resonance Direct Thrombus Imaging (MRDTI) can be an accurate test for diagnosing Upper Extremity Deep Vein thrombosis (UEDVT)
There is growing evidence that gut permeability (or a 'leaky gut') can be linked to metabolic health and might therefore be involved in development of metabolic disorders related to the metabolic syndrome. We hypothesize that gut…
Reveal common mechanisms of compulsivity in OCD and GD and disorder specific characteristics of aspects that have been related to compulsivity: confidence in relation with preference for risky and ambiguous behavior, and (negative) outcome…
During the cooling by a cold cap, the scalp is cooled to 4oC for a long period of time (30 minutes prior to start and up to 45 minutes after the infusion of paclitaxel). This could be of influence on the body temperature. Pharmacokinetics and…
Intracranial atherosclerosis is an important cause of ischemic stroke and transient ischemic attack (TIA). Ischemic stroke or TIA in the posterior circulation accounts for approximately 20 to 30% of all ischemic events. We hypothesize that arterial…
Exploratory study to develop hypotheses
Patients undergoing breast conserving surgery in combination with oncoplastic surgery are more satisfied with the cosmetic result and have a higher quality of life
Screening of esophageal cancer can be improved by the optical detection of field cancerization
The serumconcentration of ropivacaïne 10mg/ml are low after local infiltration with the standard dosis.
The use of PEG-asc could contribute a significant decrease in potassium values a potentially cause serious clinical adverse events.