628 resultaten
Casting devices such as the total contact cast (TCC), bivalved TCC, or cast shoes are commonly used offloading treatment devices. The effect of these devices on the plantar peak pressure has not been directly investigated with between-device…
1. We hypothesize that exercise training in breast cancer survivors positively affects patients quality of life, on the short- and longterm. 2. We hypothesize that the cohort multiple Randomised Controlled Trial (cmRCT) is a more suitable design for…
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
We hypothesize that patients with a HER2-negative primary tumor but with at least one HER2-positive CTC benefit from HER2 targeted treatment with trastuzumab
There seems to be a biphasic process of bone mineral density (BMD) changes in osetoarthritis (OA). An increased bone mineral density (BMD) and a specific distribution of BMD in the cortical of the subchondral plates and below in the trabecular bone…
Primary objective is to evaluate the effect of PRF treatment in comparison with neurectomy in terms of pain relief. This outcome will be measured using Numeric Pain Rating Scale 0-10 (0 = no pain and 10 = excruciating). Hypothesis: PRF as…
Several reasons for clozapine discontinuation are known, but the current evidence identifying patients who are at risk of discontinuation of clozapine is small and not always consistent. Also cultural differences may question if international…
This study investigates whether light therapy is an effective treatment for depression during pregnancy. Secondly, it investigates the late effects of bright light therapy on quality of sleep, endocrine function during pregnancy and birth outcome.…
In hemophilia patients arterial hypertension is more common than in de general population. The cause of this increased prevalence is unknown. Recent studies on atherosclerosis in hemophilia focused on intima lesions. However, arterial calcification…
The hypothesis is that minimal invasive surgical ablation through video assisted thoracoscopic surgey as a primary treatment in patients suffering from (longstanding) persistent atrial fibrillation is superior to transvenous catheter ablation
This study examines the interplay between adolescents’ peer relations and molecular genetics in predicting risk behaviors. The central question is: How do molecular genetic information and peer dynamics interplay in explaining adolescent risk…
Non invasive hemodynamic monitoring is as good as invasive monitoring
Custom made orthotic insoles by a podiatrist are (cost)effective in reducing pain and improving function in patients with plantar fasciitis compared to sham orthotic insoles and education alone.
It is hypothesized that implementation of the MASS protocol in IVE schools will increase the chances of obtaining a degree and a better chance of work employment in later life. An adequate approach to absenteeism using the MASS protocol at IVE…
The aim of this study is to investigate the effectiveness of a brief computer intervention to improve body satisfaction and self-esteem in a clinical population of adolescents with an eating disorder. We will examine whether the intervention is…
We hypothesize that there is no difference in survival, clinical and radiological follow-up after >12 years of follow-up between the scarf and chevron osteotomy.
To determine the frequency of the most common causes of hospitalizations abroad, repatriation or death of Dutch business and leisure travellers in recent years to identify risk groups for serious health problems.
The optimal feeding route has yet to be found(1). A nill by mouth regime is generally applied after an esophagectomy. However, early oral feeding has been shown to be feasible and safe (NUTRIENT 1). This study will investigate the best feeding route…