1343 resultaten
Gut-homing lymphocytes play a role in the development and maintainence of perianal fistula in Crohn's disease patients.
H1: the exercise intervention is effective in reducing (work-related) fatigue H2: the exercise intervention is effective in improving (work-related) self-efficacy, sleep quality, work ability, cognitive functioning, and aerobic fitness.
Delegation of clozapine monitoring tasks to a Nurse Practitioner (condition A) is at least as safe as Treatment As Usual: physicians perform monitoring tasks themselves (condition B).
About 10-15% of the population suffers from chronic insomnia. Structurally poor sleep can have unpleasant consequences for people's health and quality of life. Therefore, proper treatments are of great importance. Fortunately, Cognitive…
Deep brain stimulation (DBS) targeted at the ventral anterior limb of the internal capsule (vALIC) is an effective treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, effective DBS for these patients requires relative…
Parenting is essential for the upbringing of social, mentally and physically healthy children. Parenting interventions can support parents in this process. In general, parent training programs have a positive influence on various outcomes related to…
Nicardipine might decrease adverse maternal and neonatal outcome due to its pharmacokinetics and fewer side-effects.
Children aged 4 to 6 years in the intervention group who have received the GigaGaaf! intervention have a different oral health than children aged 4 to 6 years from the control group who have received care as usual. Parents of the children aged 4 to…
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
Given the high prevalence and burden associated with sexual problems and the existence of barriers to seek treatment among gynaecological cancer patients, there is a clear need for a brief, inexpensive and effective psychosexual rehabilitation…
The main objective of this study is to investigate the effectiveness of BEAR (a parent training combining e-learning and home visits) compared to care-as-usual (CAU) in young children (12-30 months) who are at risk of developing ASD, in a cluster…
We hypothesize that implementation of the new post-transplantation program will result in: - Decreased renal function decline (improved graft survival) - Improved medication adherence - Improved tacrolimus exposition - Improved feeling of patient…
It is hypothesized that the E-health self-management treatment results in lower impact of the disease on daily life, primarily a lower level of distress, in comparison to care as usual. As secondary objectives the effectiveness of the treatment on…
The aim of the study is to investigate the effect of conditioning with exogenous oxytocin on endogenous oxytocin release in healthy participants. We hypothesize that conditioning will lead to altered oxytocin levels.
Targeting a higher SpO2 (95% lower limit) in children with moderate-severe BPD from 36 weeks PMA and onwards, will possibly lead to superior growth of normal lung tissue (assessed indirectly by body weight) at 6 months corrected age, compared to a…
Rehabilitation on skates after ACL reconstruction is non inferior to current common practice.
The objective of this proof-of-concept study is to test the feasibility of the gamma-prototype of the lower limb exoskeleton XoSoft during locomotion-tasks related to daily life in stroke and incomplete spinal cord injury patients in a controlled…
Our primary objective is to compare the short and medium term (up to 6 months) clinical results in pain and function of the Bauerfeind SecuTec OA brace with only conservative treatment (no brace) in the management of patients with medial knee OA and…