2746 resultaten
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
"Het primaire doel van het onderzoek is het evalueren van de fixatie en migratie patronen van de Persona Partial Knee (Zimmer Biomet, Warsaw, IN) in vivo, met model-based RSA. Het secundaire doel van het onderzoek is het analyseren van de korte…
Dental caries lesions (with ICDAS Codes 3 and 4) can be treated by sealing, offering a less invasive and less costly treatment option with the same results as preparation and restoration of the carious lesions.
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
Vernakalant is superior to Amiodarone and rate control alone in the acute conversion of recent onset atrial fibrillation (AF) in critically ill patients admitted to the medical ICU.
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
Primary: are there differences between the online course group and the control group in the change in depressive complaints from baseline to follow-up measurements? Secundary: Is the intervention cost-effective compared to a no preventive…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral teacher training techniques for teachers of children attending regular primary school (class 3 to 8, six to thirteen years old) with (…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
Isolated liver perfusion has the advantage of controlling liver disease and decreasing treatment related symptoms and complications. This phase II trial aims to study the effectiveness and safety of the PHP treatment with Melphalan in patients with…
Patient with isolated resectable colorectal peritoneal metastases (PM) have a 3-year overall survival of 50% after upfront cytoreductive surgery with HIPEC (CRS-HIPEC) alone, and a 3-year overall survival of 65% after perioperative systemic therapy…
The hypothesis is that repeated remote ischaemic postconditioning (by improving vascular, immune and anti-inflammatory pathways) will minimize infarct size and, subsequently, will improve clinical outcome in stroke patients.
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It is hypothesized that respiratory depression from the opioid oxycodone will increase with concomitant administration of alcohol. Furthermore it is hypothesized that the increase in respiratory depression is not only dependent on the dosage of…
It is hypothesized that use of the 'Versterk je Enkel' App will increase compliance to the neuromuscular program and, consequently, will decrease ankle sprain recurrence incidence.
We hypothesize that the course of the disease can be shortened with MUA with a quicker functional recovery and gain in range of motion and a subsequent faster return to work compared to conservative treatment.
By reducing the interval between thyroidectomy and radioiodine ablation therapy in patients sick leave time of the patients can be reduced and the quality of life improved. Furhermore costs will for society will be lower.
The MAD is effective in reducing seizure frequency in patients with refractory epilepsy and severe intellectual disabilities.
ARA 290 improves neuropathic symptoms in patients with type 2 diabetes.