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This reduced intensity protocol is instituted to: 1. Confirm the data obtained in the SNWLK-ALL-6 protocol for standard risk patients; 2. Offer significant improvement of cure rate in high risk patients, comparable to international childhood ALL…
Conditions during an IVF procedure might interfere with fetal growth and development and thereby permanently influencing the programming of organs and their function.
1. In patients with a painful arc, treatment with hyaluronic acid and lidocaine, will give a mean improvement of 70 % of their pain at 26 weeks after start of the treatment with subacromial injection as compared to subacromial injection with a…
1. Earlier identified differences in functional ability and radiological damage progression are maintained in the next ten years; 2. Early suppression of disease activity results in long term improvement in functional ability and suppression of…
Dose-escalation of paroxetine (up to 50 mg/day) does not increase efficacy of treatment of Major Depressive Disorder in patients who did not respond to a 6 week trial of paroxetine in a standard dose (20 mg/day).
A trauma care strategy involving early shockroom CT scanning with a standard diagnostic imaging strategy in trauma patients has a positive effect on both patient outcome and operations research.
Does the use of alternatives to allogeneic blood (erythropoietin or reinfusion of autologous shed blood intra- and/or postoperatively) for patients undergoing elective total knee- or hip replacement surgery lead to continuous sparing of allogeneic…
Elevated levels of Free Fatty Acids during fasting induce oxidative stress and cause insulin resistance to maintain euglycemia.
We hypothesize that without continuous EEG registration, subclinical electrographic seizures will be missed. Repetive ictal seizures and a sublcinical status epilepticus may be deleterious to the immature brain. On the other hand the use of…
To compare the effectiveness of clomiphene citrate with metformin versus clomiphene citrate only in women with newly diagnosed polycystic ovary syndrome with respect to ovulation, pregnancy and sponteneous abortions.
Counteract the process of cognitive impairment in elderly people with mild vitamin B12 deficiency through oral supplementation with vitamin B12 or a combination of vitamin B12 with folic acid.