70 resultaten
Low molecular weight heparin plus aspirin reduces the recurrence of preeclampsia and/or small for gestational age infants before 34 weeks gestational age in women with documented thrombophilia with a history of preeclampsia and/or small for…
1. In patients with a painful arc, treatment with hyaluronic acid and lidocaine, will give a mean improvement of 70 % of their pain at 26 weeks after start of the treatment with subacromial injection as compared to subacromial injection with a…
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
1. Can a larger percentage of Low SES women with depressive and/or stress related symptomatology be reached with an intervention when this contains an exercise component? 2. How effective is exercise only (B) compared to a control group (C) and does…
To provide evidence that restoration of euthyroidism (normal TSH) improves thyrotoxic symptoms and signs and quality of life and lowers the risk of subsequent atrial fibrillation and bone loss in subjects with endogenous subclinical hyperthyroidism.
Test in a phase III randomised study whether an improvement of loco-regional control can be obtained with accelerated postoperative radiotherapy (66 Gy in 5 weeks) as compared to conventionally fractionated radiotherapy (66 Gy in 7 weeks) in…
10 Gy additional boost to the tumor bed will yield an increase in local control at 10 years from 88% to 93%, with still acceptable cosmesis.
Due to tumoricidal effect of PDT , it is expected that the central bile ducts remain free from tumor and so better and prolonged drainage can be achieved leading to beter QoL and survival.
The hypothesis is that cummulative doses of 2.5, 5.0 or 7.5 gram methylprednisolone infusions are equally effective in moderately severe Graves' ophthalmopathy, but that the doses differ in the number and severity of side effects.
Intrapartum fetal monitoring with the STAN-method (cardiotocograpy with ST-analysis of the fetal ECG) results in less neonates with metabolic acidosis and less interventions for fetal distress as compared to monitoring with cardiotocography in…
To compare the efficacy and tolerability of immediate optimal endocrine adjuvant therapy versus standard chemotherapy (5 endocrine therapy in pre- and perimenopausal patients with ER and/or PR courses FE90C) followed by the same positive primary…
Dexamethason pulse therapy is saver and as good as/or better than treatment with prednisone in patients with myositis.
Targets of blood pressure, glucose and cholesterol are better feasable with rosiglitazone and structured treatment advice.
Antioxidants or anticytokines may suppress the autoimmune reaction in orbital tissues in Graves' orbitopathy patients. Nul hypothesis: selenium and pentoxifilline are as effective as placebo in mild Graves' orbitopathy.
1. The incidence of falls in the elderly can be reduced by identifying elderly at high risk of falling followed by a systematic multidisciplinary examination of the causes of faling and by taking tindividual preventive measures (transmural health…
To investigate whether a strategy of direct stenting without pre-dilatation is associated with a reduced incidence of restenosis at 9 month follow-up angiography, compared to conventional stenting with pre-dilatation or compared to a strategy of…
Intervention with the recently developed COPCA method improves developmental outocme at 6 and 18 months more than traditional types of early physiotherapeutical intervention.
Non-inferiority hypothesis: observation is not inferior to operation with respect to the mean of pain and discomfort during 3 years follow-up.