821 resultaten
Intra uterine exposure to anti-TNFα inhibitors influences the normal development of the immune system, leading to immunodeficiency and immune dysregulation, with the potential to cause short term and long-term morbidity. TNFα plays an important role…
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.
The hypothesis is that twins discordant for pregnancy complications display a distinct epigenetic signature in MSCs. This signature contributes to cellular metabolic alterations and is associated with future cardiovascular and neurodevelopmental…
This project aims to investigate the feasibility and oncological safety of eFTR as minimal invasive completion treatment following previous incomplete endoscopic resection of low-risk T1 CRC.
Not applicable
The goal of the proposed study is to test the null hypothesis that vaccination will not boost the cytotoxic T cell responses against UTA2-1 in >20% of the patients.
Combining digital FDG-PET/CT and DW-MRI imaging will more accurately predict and define response in rectal cancer patients after neoadjuvant treatment.
Very limited treatment options are available with a rapid onset to counter off periods in Parkinson’s disease patients. Therefore, the development of rapid onset levodopa formulations is warranted, for which an inhalable formulation of levodopa is…
In terms of effectiveness, we hypothesized that for each patient during treatment: 1 Compared to a waiting list baseline, the intensive inpatient treatment with adapted ST interventions together with ST milieu therapy during 12 weeks results in…
Primary Objective: to compare the effects of two interventions on lifestyle behaviour (food intake and physical activity) and quality of life in people with T2DM: the NDC and a combined lifestyle intervention, namely the NDC with addition of a self-…
The pharmacokinetics of erlotinib 150mg QD is comparable to the pharmacokinetics erlotinib 75mg + ritonavir 200mg QD.
Based on recent data derived from animal research in combination with earlier clinical trials, we hypothesize that stimulation of cerebellar nuclei in pediatric refractory epilepsy patients might be effective in significantly decreasing epileptic…
1. Post-migration stressors are associated with parental self-efficacy controlling for war-trauma 2. Parents feel more efficacious on days with less post-migration stressors and vice-versa 3. Real Tailored Verbal feedback on parenting will improve…
PPI administration to women with confirmed PE lowers sFlt-1 levels and which may lead to less complications or progression of disease.
It is hypothesized that a higher protein intake has a beneficial effect on bone and muscle health outcomes and subsequently leads to a shorter rehabilitation time.
This study aims to underpin the delivery of longstanding exercise therapy in the subgroup of patients with axSpA and complex disability. There are 3 research questions to be addressed: 1. Is longstanding, optimized active exercise therapy more…
N/A
Switching to sarilumab in patients with rehumatoid arthritis responding well to tocilizumab does not lead to a relevant increase in disease activity and is feasible with a persistence of sarilumab >70% at 6 months