2194 resultaten
To prospectively study if patients carrying clinically relevant DPYD variants (DPYD*2A, c.2846A>T, c.1236G>A/HapB3, c.1679T>G) are more at risk for developing moderate/severe vesicles or bullae with 5-FU cream.
In deze studie onderzoeken we hoe in het eerste jaar na de niertransplantatie bij kleine kinderen de hartfunctie zich aanpast aan de toegenomen bloedstroom-vraag. Ook onderzoeken we hoe de doorbloeding van de relatief grote nier zich ontwikkelt.…
What are the health effects of first time running a marathon ?
The influence of the use of a web-based application on the patient satisfaction by eduction to patients with breast cancer.
IgG4-associated cholangitis mimicks perihilar cholangiocarcinoma, resulying in patients being resected for benign disease
Informed consent procedures and information provision differs between different transplantation centers and transplantation professionals in The Netherlands. Donor knowledge and satisfaction may be influenced by the manner of information provision…
It is hypothesized that the benefits of treating to target in early RA and UA, which were evident after 5 (IMPROVED study) and 10 (BeSt study) years as limited joint damage progression, good functional ability and (in BeSt) normalized survival at…
We hypothesize that the use of a modified CellSearch enrichment method will specifically detect MPM tumor cells in the pleural effusion and peripheral blood of patients with MPM
In 2011, thirty-four major liver resections (resection ≥3 segments) were performed in the AMC. The outcome of these hemihepatectomies has improved in the last years because of better surgical techniques and postoperative care. Nevertheless, there is…
It has been demonstrated that VATS is a good alternative treatment option for chest drainage in children with parapneumonic effusion. Clinical improvement even seems to occur faster after VATS, indicating that when VATS is performed in an early…
We hypothesize that anxiety symptoms worsen after follow-up imaging compared to patients baseline anxiety levels.
The hypothesis is that children who are exposed to anti-TNF during pregnancy, and who are subsequently born with significant anti-TNF levels detectable until at least 3 months of age, will insufficiently generate an adequate immune response (anti-…
Rheumatoid arthritis patients have an increased risk on developing cardiovasculair disease compared to healthy controls. In this study we explore the influence of disease actitivity on certain cardiovascular parameters (glucose intolerance; lipids;…
For patients with a diffuse large B cell lymphoma (DLBCL) the efficacy of the anti-CD20 monoclonal antibody rituximab combined with salvage chemotherapy in the second-line setting has decreased due to more effective first-line treatment with…
Better knowledge and awareness of Late Effects after pediatric HSCT for non-malignant diseases will lead to optimal screening procedures after HSCT that may eventually contribute to reduce transplant-related long term morbidity and mortality and…
To assess whether the genetic architecture of this severe therapy-resistant SCZ phenotype differs from the broad DSM-based SCZ phenotype.
N/A
The improved fibrin generation test, and other biomarkers are predictive for venous thromboembolism in cancer patients
Does sildenafil improve tumour perfusion?
A mathematically correct PK-PD model will be developed that describes the depressant effect of propofol on breathing with and without a background of remifentanil.