610 resultaten
To prospectively study if patients carrying clinically relevant DPYD variants (DPYD*2A, c.2846A>T, c.1236G>A/HapB3, c.1679T>G) are more at risk for developing moderate/severe vesicles or bullae with 5-FU cream.
Training therapist in optimized ROM (Feedback Informed Treatment) and Shared Decision Making will result in less drop-outs, better outcomes, better patient experience and more favourable attitude ot therapist towards Routine Outcome Monitoring
The YEARS algorithm is non-inferior to management by CTPA with regard to 3-month recurrent VTE rates and will reduce the rate of unnecessary CTPA in patients with clinically suspected PE and active malignancy.
Erythromycin significantly increase the pharmacokinetic exposure of palbociclib
We hypothesize that acute fear, induced by watching a scary movie, increases platelet activability.
The improved fibrin generation test, and other biomarkers are predictive for venous thromboembolism in cancer patients
Pain perception during infiltration of Lidocaine/Adrenaline for upper blepharoplasty at 37°C is reduced relative to infiltration at 21°C.
The primary hypothesis for this data collection study is that there are various surrogate physiological parameters for inferring blood pressure (BP), which can be more easily obtained than the direct BP measurement. An example of such surrogate…
By measuring biomedical variables, such as movement, temperature, heart rate variability, blood volume pulse and skin conductance, by means of a wearable (wristband), stress-related parameters can be measured easily and continuously. It is…
The Elucid Pill Connect system dispenses all doses correctly and sends accurate data to the monitoring server that represents the subject’s non-adherence whilst enforcing the dose schedule.
Topical benzoyl peroxide, applied on 5 consecutive moments by participants with positive baseline cultures for C. acnes, will reduce the number of positive skin cultures with 50% or more
CMC subtypes matter in the therapy response to systemic chemotherapy for patients with high risk stage II and stage III colon cancer
This study aims to underpin the delivery of longstanding exercise therapy in the subgroup of patients with RA and complex disability. There are 3 research questions to be addressed: 1. Is longstanding, optimized active exercise therapy more…
A 16-week multidisciplinary lifestyle program, based on (1) a WFPD, (2) exercise and (3) stress management H0: has no effect on the disease activity in patients with rheumatoid arthritis, in comparison with usual care. H1: lowers disease activity in…
A newly developed artificial saliva spray (Novospray) alleviates the feeling of a dry mouth in patients suffering from xerostomia better than placebo.
YP Face IT is effective at reducing social anxiety and improving body esteem
The primary aim of the RCT is to evaluate the effect of a guided self-help resilience training for pregnant women with depressive symptomatology on maternal depressive symptoms and resilience and secondary outcomes including maternal psychosocial…
The Trachospray device gives complete anesthesia of the airway
The procoagulant state seen in patients with hiv can be a result of the immune activation due to the hiv infection itself or combination antiretroviral therapy (cART). In case the acquired thrombophilia is a result of immune activation, the…
we hypothesize that thermal comfort and sensation will stay within similar ranges in both conditions (based on a previous study);