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1. To assess the safety and tolerability of different doses of a single IV injection of OTL-038 2. To assess the efficacy of ascending doses of a single IV injection of OTL-038 in detecting ovarian, renal cell or endometrial cancer during surgery by…
Children and adolescents with acquired brain injury who receive the computer-based cognitive retraining combined with the explicit strategy instruction will show significantly more improvement of cognitive functioning (i.e., attention, working…
Half dose Urokinase (50.000IE/h) will significantly reduce hemorrhagic complications compared with the standard dose Urokinase (100.000IE/h) with comparable technical success rate
Better and faster recovery of arm/hand for patients treated with rTMS
To assess in a randomized comparison the effect of Ibrutinib added to 10-day decitabine treatment on the cumulative CR/CRi rate after 3 cycles. To assess the safety and tolerability of Ibrutinib added to 10-day decitabine treatment for AML (…
1.Potentially transplantable high risk donor liver grafts can be distinguished from non-viable high risk donor liver grafts using NMP. 2.DHOPE, prior to ex situ viability assessment, increases the odds of a high risk donor liver graft to be…
The aim of this study is to examine whether the implementation of a redesigned intake process using e-health is effective compared to the intake as usual without an e-health intervention. The first hypothesis is that using e-health in a new intake…
The use of motivational counselling and inclusion of a written health plan in an occupational health examination will improve personal work resources and work ability at 12 months follow-up
Treatment of fear of falling in hip fracture patients in GR, using the FIT-HIP intervention, will lead to reduction of fear of falling and therefore to an improvement of mobility function (gait and balance), in comparison to patients with fear of…
We believe we can extend current insights into the effectiveness of nudging by examining neural correlates in two specific areas important for choice architecture; the role of social influence, and the role of color cues in product evaluation and…
Stromal Vascular Fraction enriched lipofilling in combination with Platelet Rich Plasma (PRP) increases skin quality improvement as compared to lipofilling in combination with PRP alone.
Patients will improve significantly on OCD symptoms and general functioning.
The detection rate of leptomeningeal metastases with the CellSearch technique is higher compared to cytology.
Rationale: Irregular menstrual cycles during puberty have been considered part of development, explained by incomplete maturation of the hypothalamic-pituitary ovarian axis. A distinction between developmental and pathological causes of abnormal…
Virtual Reality (VR) as distraction technique is promising as pain relief. The extent to which VR is effective in relieving pain depends on the extent of presence in the virtual world. This study investigates if the quality of different executive…
It is hypothesized that a preoperative oral antibiotic prophylaxis, that is administered in addition to perioperative intravenous prophylaxis, will lead to a reduction in postoperative would infections after colorectal surgery
In normal weight and overweight/obese young males we expect that - when compared to a single bout of prolonged sitting: (1) sitting on a stability ball will attenuate cardiometabolic health effects; (2) 10-min standing interruptions will not…
The aim is that Pluspraktijken result in lower health care costs compared with usual care, while maintaining or enhancing the health status and experience with care of the patients.
Early nutrition in preterm infants is essential for growth and neurodevelopment. The last decades more aggressive nutrition has been implemented in clinical practice to ensure optimal growth and thereby optimal neurodevelopmental outcome, as…
Patients undergoing breast conserving surgery in combination with oncoplastic surgery are more satisfied with the cosmetic result and have a higher quality of life