444 resultaten
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius fracture.…
By developing a model which predicts the risk of bleeding with coumarin use, patients can be treated more effectively, potentially avoiding the need for specific antidotes. Besides decreasing the risk of bleeding (potentially resulting in less…
Giving smokers (who are motivated to quit smoking) an attentional retraining to train away the attention they have for smoking related stimuli will be significantly more effective in preventing smoking relapse than giving them a non-training version…
To assess the tolerability and efficacy of the addition of oral tosedostat to standard induction therapy.
Feedback to the COPD patient about his condition and physical activity plays an important role in promoting self management. Within the current care for patients with COPD, there is a lack of insight into daily activities and lack of understanding…
The aim of this project is to determine optimal communication strategies for prognostic disclosure in the palliative phase of breast cancer from a patient perspective. Study 1: To explore breast cancer survivors’, healthy women’s and oncologists’…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
Several new imaging techniques have been developed in order to improve differentiation of colonic lesions, one of these is confocal endomicroscopy. The objective of the proposed study is to evaluate the feasibility and additional value of confocal…
An effective intervention towards stopping passive smoke exposure in children is possible by means of an individualized program with repeated counseling, education, motivational interviewing, and by promoting parental awareness with feedback about…
The general objectives of this study is to test whether estrogens and androgens in both males and females affect cognitive functions and brain activity.
An ICT-supported, integrated, multidisciplinary treatment of COPD in primary care compared to usual care in primary care practices will improve the quality of life of COPD patients at an acceptable level of cost-effectiveness.
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
To gain more insight into the pathogenetic processes involved in Sjogrens Syndrome(SS) bij analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and…
Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij baarmoederhalskankerpatienten.
Fluorescent near-infrared imaging can accurately detect sentinel lymph nodes non-invasively during lymphadenectomy in cervical cancer patients.
Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.
To determine if zinc supplementation in AMD patients has a direct measurable effect on the complement system explaining the mechanism through which this substance exerts its influence on AMD progression.
Chronic heart failure (CHF) is a clinical syndrome resulting from a decreased cardiac output, insufficient to maintain adequate tissue oxygenation. As a consequence, CHF patients suffer from fatigue and exercise intolerance. It is widely recognized…
Geriatric assessment at hospital admission followed by intensive home follow up by a community care nurse will reduce the rate of functional decline six months after admission in acutely hospitalized patients of 65 years and above.
1. Examine the reproducibility of the non-volitional endurance test in healthy subjects. The hypothesis is that the non-volitional endurance test is reproducible; 2. Comparison of muscle endurance tested at three different stimulation intensities.…