377 resultaten
To evaluate the safety and tolerability of AP30663 in healthy males at doses up to 12mg/kg
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
Our hypothesis is that the efficacy of FMT in patients with active UC can be increased by: 1. Pretreatment with budesonide in patients with active UC, which may reduce inflammation prior to infusion of the donor feces solution. This reduced…
We expect to find that e-liquids with nicotine salts taste milder and are easier to inhale than e-liquids with free-base nicotine. More specifically, we hypothesize that e-liquids with nicotine salts, in comparison to free-base e-liquids: 1. are…
Onderzoeken of drie weken lang CBD spanningsklachten kan verminderen bij hersentumorpatiënten in de stabiele fase kan verminderen, en zo kwaliteit van leven kan verbeteren. Depressieve klachten, slaap/vermoeidheid en algehele kwaliteit van leven…
Sacrificing the chorda tympani causes less taste disfunction than stretching or damaging the chorda tympani nerve.
By dosing Ampligen every other day intranasally, it is believed that SARS-CoV-2 can be inhibited at the point of entry, and thus will be much less likely to progress to a pulmonary infection, or moderate COVID-19 disease.
Trend analyses Of Patient-Specific respiratory Physiologal INteractions for weaning decision support
Difficult to wean patients have a mismatch between optimal mechanical ventilation settings lung mechanics and respiratory muscle dynamics
The test product supports normal physical growth in healthy term infants
To investigate the safety, tolerability and pharmacokinetics after multiple daily doses of YTX-7739
We hypothesize that treatment with Tapentadol will reduce the development of chronic postoperative pain by enhancing or maintaining CPM responses and possibly reducing central sensitization. We hypothesize that a 4-week treatment with Tapentadol…
The course of resting energy expenditure (REE), measured by indirect calorimetry changes based on standard versus high enteral protein feeding in the ICU.
The aim of this study is to prospectively assess the efficacy of LDN as induction therapy in CD.
To generate proof that convalescent antibody-mediated treatment of ICPs, who suffer from COVID-19 disease can protect ICPs from a more severe course of disease.
Primaire doelen: 1. de uitvoerbaarheid van FMT bij patiënten met de zvP beoordelen 2. de veiligheid van FMT bij patiënten met de zvP beoordelen. Secundaire doelen: 1. Bepalen of FMT op lange termijn (tot 12 maanden na FMT) leidt tot…
1. We hypothesize that the ingestion of 30 g of collagen peptides and 30 g of free amino acids (matching the profile of collagen peptides) will result in greater myofibrillar and connective tissue protein synthesis rates in skeletal muscle tissue at…
Primary To characterize systemic and local KLH-specific B and T cell responses by repeated KLH immunizations Secondary To characterize the molecular basis of the KLH-driven skin response (acute versus delayed response, Th1 versus Th2 response) To…