375 resultaten
The main objective of the study is to investigate if positional therapy during sleeping, using the LEFT device, reduces nighttime gastroesophageal reflux symptoms.
The hypothesis is that random assignment to C1-INH in patients with moderate and severe TBI will experience a reduction in ICP directed therapy intensity levels (TIL) compared to random assignment to placebo (difference of 2.2). Secondary, if…
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
Low-load blood flow restriction therapy has beneficial effects on postoperative quadriceps and hamstrings atrophy/strength, at 8 and 14 weeks after bone-patellar tendon-bone anterior cruciate ligament reconstruction, compared to standard care…
We aim to test the hypothesis that increasing excitability of the cerebellum – through cerebellar tDCS – improves also the non-motor features of cerebellar disorders, and more specifically CCAS, in patients with cerebellar disorders. If we are…
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
The main hypothesis of this study is that a promotional campaign targeting both KHOA patients and health care providers ultimately impacts patterns of healthcare consumption (Panagioti et al., 2014), i.e. delay referral to secondary care.
Primary Objective To evaluate the safety and tolerability of topical XZ.700 in patients with mild to moderate atopic dermatitis Secondary Objectives To investigate the PD effects of XZ.700 in patients with mild to moderate atopic dermatitis To…
The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
2gr of Cefazolin is effective as prophylaxis for surgical site infections following implant removal below the level of the knee.
We hypothesize that among breast cancer patients with a grade 3 breast fibrosis the RILA frequency is significantly lower compared to the RILA frequency among breast cancer patients with no fibrosis.
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
We hypothesize that the number of patients without vertigo spells at 12 months follow up will be higher in the group that has undergone EDB than in the decompression group.
The objective of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of ALKS 6610 after single ascending oral doses in healthy adult subjects.
This study will investigate the potential of EDP1815 to modify the immune system through a Keyhole Limpet Haemocyanin (KLH) challenge. Furthermore, safety and tolerability of multiple oral doses of the monoclonal microbial EDP1815 will be assessed…