369 resultaten
We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
Tropicamide is less effective in inhibiting accommodation and has a small window of maximum activity. Cyclopentolate is more effective but in darker pigmented subjects a significant residual accommodation can be present. Children often show…
Perioperative esmolol infusion titrated for heart rate control as an add-on to standard therapy including a long acting oral beta-blocker will improve heart rate control and decrease perioperative myocardial ischemia, without an increase in…
Different dietary proteins have a different effect on blood pressure-related mechanisms.
Prolonged antibiotic treatment of patients diagnosed with presumed PLD (as endorsed by the international ILADS guidelines) leads to better patient outcome than short-term treatment as endorsed by the Dutch CBO guidelines.
We hypothesize that supplementation of high doses of vitamin D in non-atopic asthmatic patients can reduce neutrophilic and/or eosinophilic airway inflammation.
The present study will investigate how serotonin (manipulation via ATD) modulates psychological and physiological reactions to interpersonal stimuli in individuals at risk for MDD. This is relevant for several reasons: 1. The onset, severity, and…
A positive effect of the investigational product on the intestinal microbiota of healthy Asian toddlers is expected.
Geriatric assessment at hospital admission followed by intensive home follow up by a community care nurse will reduce the rate of functional decline six months after admission in acutely hospitalized patients of 65 years and above.
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The TENLEP Trials proposal builds on the findings of the INFIR Cohort Study and the recommendations of the NLR-funded international Workshop on Neuropathology in Leprosy in the Netherlands in 2007. At this workshop, several key research questions…
Based on its general pro-hemostatic potential, prothrombin complex concentrate may be effective in (completely or partially) reversing the anticoagulant effect of the new antithrombotic agents Dabigatran and Rivaroxaban.
We want to establish intero-interoceptive conditioning in healthy volunteers for the better understanding of the development of panic attacks into panic disorder.
Type 2 diabetes patients frequently suffer from physical deconditioning and vascular disease. Although the exact mechanisms are unclear, microvascular changes and endothelial dysfunction appear to inhibit the oxygen transport and uptake in…
Our hypothesis is that the extravesical technique reduces the incidence of PCN placement, and urological complications.
Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius fracture.…
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
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We hypothesize that US-guided treatment (barbotage) in combination with corticosteroid injections gives better short-term clinical and radiographical results, compared to treatment with solely corticosteroid injections. Secondly, we expect that…
Dietary management with the medical food under study has a positive effect on muscle strength and physical functioning in elderly.