208 resultaten
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
The overall aim of this RCT is to examine whether an individual music intervention can improve the challenging behavior, quality of life, emotional wellbeing and EF of adults with a mild to moderate ID.
Too little is known about patient preferences on (self management) education during the 4 to 6 weeks after total knee replacement surgery. We hypothesise this study will provide us with valuable insights on their preferences: type of information (…
-The combination of center-based CR and a home-based exercise training program will lead to a greater increase in physical activity levels compared to standard care. -Continuation of home-based exercise during a three-month follow-up will lead to…
Young people with a psychotic disorder have the same social goals as their healthy peers, but their social networks are smaller, they participate less often in leisure activities and are less successful in work and education. This impairment in…
We aim to evaluate the efficacy of the `OncoSTRIP', a standardized polypharmacy assessment method, in a group of elderly patients with cancer on medication use satisfaction by using the 'Treatment Satisfaction Questionnaire for Medication…
The precise mechanisms driving onset and course are insufficiently understood, disease progression from a current patient state and/or the development of comorbidities are unpredictable, and the optimal type and time-point for intervention is as yet…
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
Neither data on patient preferred attributes specific for type 2 diabetes nor a validated patient decision aid to support healthcare providers is available in the Netherlands. The aim of this study is to collect and generate patient-preference data…
Ayahuasca significantly modulates high-level network functional connectivity and neurometabolite concentrations when compared to baseline.
Patients with a discrepancy between between painful-to-swollen joints have a lower score on pain sensitivity measurements (PPT, EPT and NDT) and a higher score on questionnaires (CSI, GPQ, SFD-36 and PCS).
The prevalence of HIV and STDs (Hepatitis B/C/ Syphilis/ Chlamydia/ Gonorrhea) in the adult transgender population in the Netherlands is lower than the global reported prevalence of these diseases.
Early post-operative mortality is particularly high, with reported 30-day mortality rates of 7.5 - 13.3%. Up to 5% of the hip fracture surgeries is performed in patients with a high death within 30-days after surgery. If the preoperative mortality…
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
It is expected that functional status and health status is impaired in COVID-19 patients after hospital discharge and that this will improve after a multidisciplinary rehabilitation program.
TKR with large migration in the last 2 PO years show a larger inducible migration compared with TKR with little to no migration in the last 2 PO years