144 resultaten
Background: Multiproblem young adults (between ages 18 and 27), characterized by a variety of severe psychosocial problems, comprise a societal challenge with high priority on the political agenda, both nationally and internationally. However, so…
Null hypothesis: the 8 centres with different cardiac rehabilitation (CR) programmes do not differ from each other with regards to the effectiveness.
Non invasive hemodynamic monitoring is as good as invasive monitoring
Custom made orthotic insoles by a podiatrist are (cost)effective in reducing pain and improving function in patients with plantar fasciitis compared to sham orthotic insoles and education alone.
The aim of the current pilot study is to investigate the prevalence of (symptomatic) hypoglycaemia in frail elderly patients with type 2 diabetes treated with sulfonylurea and metformin, and to gather data for a full-scale hypothesis-testing study.…
The optimal feeding route has yet to be found(1). A nill by mouth regime is generally applied after an esophagectomy. However, early oral feeding has been shown to be feasible and safe (NUTRIENT 1). This study will investigate the best feeding route…
primary: 1.CCT reduces rumination in depressed patients. secondary: 2. The effects of CCT on working memory effect generalize to other Working memory tasks (neutral and emotional). 3. CCT has an effects on the mood of depressed patients.
An expectative management ('watchful waiting') is not inferior regarding the composite of mortality and/or necrotising enterocolitis and/or bronchopulmonary dysplasia in comparison with an early treatment regime in preterm infants with a…
We hypothesize that: 1) Patients receiving an ice-lolly or chewing gum directly postoperative will have lower pain intensity scores in the 24 hours following surgery compared to no non-pharmacological treatment. 2) Patients receiving an ice-lolly or…
In this RCT we investigate the effects of two school-based physical activity interventions (aerobic exercises versus coordinative exercises) in primary school children on executive functions and academic achievement. We hypothesize that both aerobic…
Several investigators have suggested using dietary carbohydrate restriction as a therapeutic strategy to allow the host to successfully compete against a tumor [2, 7, 19]. The induced ketosis and increased lipolysis after low carbohydrate diets have…
What are the motivations of women in the Netherlands to choose UC and what are their beliefs on childbirth in general and in relation to current Dutch maternity care? This study primarily aims at understanding women’s motivations in declining (parts…
It is expected that the respiratory microbiome will be relatively stable over time in non-infectious patients.
•To assess the safety and tolerability of induction doses of ABP-700 and determine dosing regimens that reliably produce drug induced unconsciousness and the pharmacodynamic conditions necessary for induction of general anesthesia with ABP-700 alone…
Circulating tumour cells can help to diagnose Non small cell lung cancer (NSCLC), making the painful and invasive procedure of a lungbiopsy and bronchoscopy unnecesary. However, for this, we need to harvest higher amounts of CTC's and in more…
The use of atorvastatin in persons at high risk of RA is associated with a reduction in de development of arthritis
At equi-analgesia respiratory depression from oxycodone is manifold greater compared to Tapentadol
Is there a diiference in antidepressant efficacy between ECT and a combination of ECT and nortriptyline? Does combination therapy with ECT and nortriptyline result in a faster antidepressant response compared with ECT monotherapy? Does combination…