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If not well treated rheumatoid arthritis (RA) can lead to severe joint damage and subsequently functional impairment. Current treatment strategies aim at quickly lowering disease activity in order to prevent later damage. RA treatment…
We hypothesize that membrane-residing gangliosides are elevated in obese insulin resistant subjects and correlate to peripheral insulin resistance. Furthermore, we hypothesize that the perturbation of the insulin signaling cascade by elevated…
We hypothesize that children who will follow this structured functional PRE strength training program will increase in muscle strength, which accordingly will lead to functional improvement in physical functioning, but with no negative effect…
The objective of this study is to investigate whether thoracic radiotherapy can improve 1year survival in …
The main hypothesis is that normo-ovulatory women with a deleterious BRCA mutation have lower levels of AMH compared to normal controls, with at least a difference of 0.90 ng/ml, suggesting an effect size of approximately five years in menopausal…
A subset of patients with ulcerative colitis have disease limited to only the rectum. Most patients will reach remission with conventional 5-ASA or corticosteroid treatments. However, there have been few studies investigating treatment options in…
A physical reactivation program is more effective in improving physical activity behaviour, quality of life, diabetic parameters and psychosocial well being than usual care in type-2 diabetic patients.
Wet-wrap treatment with diluted corticosteroids is more effective than wet-wrap treatment with emollients only
Open Access Echocardiography will reduce costs of cardiac care and will improve diagnostics and therapy in primary care
The objective of this project is to gain knowledge about the how and when of cognitive behavioral treatment (CBT) of Axis I anxiety disorders when there is co-morbidity of an Axis II cluster C personality disorder. It tries to answer the question…
Estrogen plays an role in the dynamic changes in bone marrow adiposity.
The immune response to pneumococcal vaccination in patients after community acquired pneumonia with S. pneumoniae is different compared to pneumonia patients with another pathogen.
A failure to signal the salience, and especially the anticipation of positive events, is thought to be at the core of social-emotional apathy (SEA) in patients with schizophrenia. This salience system is highly dependent on dopamine from the…
patients with diabetic cardiovascular autonomic neuropathy are more prone to hypotension during surgery and therefore require more inotropic/vaspressor medication perioperatively
Patients who receive treatment as usual (TAU) plus mentalization-based treatment for psychosis (MBT-P) will show a greater improvement in social functioning than patients who receive TAU only. This effect is mediated by an increase of social…
The main aim of this project is to conduct a pilot randomized controlled trail (RCT) to evaluate the preliminary effectiveness and feasibility of cognitive behavioral therapy (CBT) as an intervention for relatives of long-term missing persons. The…
To demonstrate equivalency of the Cardica ™ C - Port xA anastomosis compared to hand sutured anastomoses in patients undergoing CABG with respect to 12 months patency at distal anastomosis site.
B2-agonists can increase CFTR function and improve disease parameters in patients with CF with a residual CFTR function. Multiple patient-specific parameters are important for the amount of B2-agonist induced CFTR function, measurements in organoids…
We hypothesize that there is no difference between the survival and follow of the uncemented and cemented ABG THA.