387 resultaten
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
1. Cysteine is an essential amino acid for newborn preterm infants; 2. Cysteine requirements change rapidly with postnatal age; 3. The change in cysteine requirement with age is based upon cystathionase activity; 4. Intestinal cystathionase activity…
We presume that reducing the fasting period by adding a carbohydrate drink 2-3 hours prior to surgery is a good and feasible option to decrease orthostatic intolerance and -hypotension. Moreover, the pre- and postoperative well-being is thought to…
To investigate whether the clinical outcome is similar after the implantation of the Resolute Integrity stent versus the Promus Element stent (non-inferiority test).
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
We aim to test the accuracy of Western gastroenterologists in differentiating T1 CRCs from its precursor lesions and subsequently in estimating invasion depth
N/A
We hypothesize that oral glucose intake and consequently the endogenous induced hyperinsulinemia will lead to insulin-induced microvascular dilatation in healthy normotensive subjects. Furthermore, we suggest that the insulin-mediated microvascular…
We hypothesize that Moroccan-Dutch differ from native-Dutch in stress reactivity. This difference is not explained by group differences in known non-social risk factors for psychosis. Affirmative findings in the current study would support to the…
Primary Objective: 1.To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective in reducing recurrences of PUs than only usual care in individuals with chronic SCI, who often have…
Stroke patients frequently complain of excessive fatigue, both in post-acute and in the chronic stage of their illness. The prevalence of severe fatigue is estimated between 28-73%, even in patients who seem to recover well. This may lead to…
There is no difference in radiographic parameters of immediate loading and delayed loading of single posterior tooth implants in healed sites.
Sympatho-adrenergic and hypercoagulable activity are enhanced in patients with chronic heart failure, partially mediated by common functional beta2-adrenergic receptor polymorphisms. Non-selective beta-blockers down regulate sympathetic activation…
1. Cooling to 34, 34.5 or 35°C by means of a surface cooling device, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours in awake patients on a stroke unit is safe; 2. In awake patients with ischaemic…
Suppression of SWS, without changing total sleep time, may affect total energy expenditure (TEE), activity induced energy expenditure (AEE), non-exercise activity thermogenesis (NEAT), endocrinological parameters and energy intake.
We hypothesize that children who will follow this structured functional PRE strength training program will increase in muscle strength, which accordingly will lead to functional improvement in physical functioning, but with no negative effect…
Primary objective: Does a 30-minute episode of helium breathing in humans decrease the amount of pro-inflammatory cytokines and chemokines produced in whole blood after immunostimulation ex vivo?