388 resultaten
In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
The objective is to assess which Transfusion Triggers are used in Blood-conserving Trials in Lower Limb Arthroplasty and to assess the prevalence of usage of Transfusion Triggers in time.
The scientific hypothesis of the present study is that supervised implementation of the guideline “Oral health care in (residential) care homes for elderly people” is more effective in improving oral health and oral health care of the residents when…
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
Current methods of detecting the presence and/or prognosis of prostate cancer are not optimal. New markers will provide better detection and/or better methods to determine prognosis. In addition, there are currently no methods available to properly…
Evaluate the long-term safety, tolerability and efficacy of the pediatric formulation of bosentan two versus three times a day in children with pulmonary arterial hypertension (PAH).
Video images are superior to photographs in conclusively documenting the 'critical view of safety' during laparoscopic cholecystectomy.
Unacylated Ghrelin will improve insulin sensitivity.
95% of the patients undergoing total knee arthroplasty are diagnosed with osteoarthritis. Osteoarthritis is a joint disease which is characterized by pain, loss of force and problems during activities of daily life. This can result in reduced social…
Daily conumption of a portion of 400 gram strawberries will reduce the glucose induced inflammatory response and oxidative stress in metabolic syndrome patients with impaired glucose tolerance (beginning type 2 diabetes).
The Goodpasture antigen binding protein is able to modify the activation of the immune response, therefore influencing the pathology of autoimmune diseases.
A bipolar disorder is a severe mental illness with often many consequences on daily life for patients and caregivers (family/friends). Treatment currently exists of pharmacotherapy and supportive treatment. Many patients do not respond adequately to…
To evaluate the usefulness of three near-infrared based devices for intravenous cannulation in children prior to surgery.
Flumazenil is a substrate of P-glycoprotein at the blood-brain barrier.
Participation in the COACH program has positive effects on the health of patients with coronary heart disease.
Our hypothesis is, that the extrinsic mechanism in the etiology of SIS is only valid for a subgroup of patients; complaints of SIS can be caused by 1) a pathologic pattern of arm-scapula movements caused by a disrupted balance in muscle forces,…
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The aim of this programm is to stimulate people to follow the medical instructions and therefore to optimise the rehabilitation process and the bonehealing. In this project a prototypes was fabricated and will be used in twenty patients with a…