584 resultaten
At two-year follow up, employees of the intervention schools report significantly lower levels of work stress and work stress risks as compared to employees of the control schools
Emerging techniques measuring oxidative APAP metabolites and microRNA-122 (miR-122) could make it possible to detect paracetamol induced liver injury earlier and more precisely than currently used paracetamol plasma concentrations and clinical…
Group Schema Therapy is more effective and more cost-effective than Individual Schema Therapy and than Treatment-as-Usual
Primary hypothesis: An extension of the psychotherapeutic treatment concept by animal-assisted group therapy (plus treatment as usual / TAU) lowers depressive symptomatology, possibly via increases in patients' experience of self-efficacy and…
The number of flares during tapering of biologicals in patient with rheumatoid arthritis can be reduced by using a dynamic flare prediction model
We expect that the access-related intervention rate and medical costs will be reduced by 40% when correction of vascular access stenosis is triggered by clinically apparent access dysfunction rather than by asymptomatic flow reduction detected by…
We hypothesize that the T2T strategy is superior compared to the T2S in retaining gout remission and is also more cost-effective.
It is expected that HFNC therapy will speed up the recovery of an exercise induced lung function decline. We speculate that the time to recovery to their normal lung function will be halved.
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
We hypothesize more than 90% of the participants in the in-hospital, standard-of-care follow-up will contact the hospital during the study period and 40-50% of the patients in the patient-led, home-based follow-up will contact the hospital between…
The primary research questions are: 1. To what extent does a 4 week ReHab-TOAT regime lead to improvement of arm function in chronic stroke patients with either a severely or moderately affected arm-hand? 2. To what extent is any improvement of arm…
We hypothesize that the combination of both the IPS and PA intervention is more effective than each of the interventions separately (IPS, or PA), i.e. ‘1+1 = 3’
Type 2 diabetes have altered chemosensitivity and are in fact sympathetically overactive compared to healthy controls during a hyperinsulinemic euglycemic clamp.
We aim to investigate whether a preoperative fasting diet reduced postoperative fatigue at 4 weeks after living donor nephrectomy in adult patients
It is unclear if DOACs are superior or inferior compared to VKAs in CTEPH/CTED patients regarding (peri-procedural) bleeding and long-term (thrombotic) complications.
We hypothesise that patients in the intervention group will show a reduction in sedentary time of at least 60 minutes per day after the cardiac rehabilitation program, compared to a reduction of maximally 30 minutes per day in the control group.
Investigate the influence on the hard and soft tissues of immediate placement of a single implant in an extraction socket in the anterior maxilla. Null hypothesis: is that there are no differences in the hard and soft tissues and aesthetic outcome
The intradermal vaccination of a fractional dose of mRNA-1273 LPN vaccine (Moderna) is safe and non-inferior in eliciting neutralizing antibodies against SARS-CoV-2 to the standard dose injected intramuscularly
Plasma presepsin level can differentiate between bacterial and viral infections in young infants with fever of unknown origin
We hypothesize that two additional face-to-face counseling sessions, in which several psychological techniques will be practiced, will support the participating patient-couples towards a significant and more sustainable lifestyle change compared…