5226 resultaten
The aim of the study is to investigate the effect of conditioning with exogenous oxytocin on endogenous oxytocin release in healthy participants. We hypothesize that conditioning will lead to altered oxytocin levels.
Part 1 Single Ascending Dose (SAD) - To evaluate the safety and tolerability of a single oral dose of prodrug, ABX-002, in healthy adult subjects Part 2 Multiple Ascending Dose (MAD) -To evaluate the safety and tolerability of once daily oral…
The objective of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of ALKS 6610 after single ascending oral doses in healthy adult subjects.
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
rTMS suppresses neural circuits using a pulsed magnetic field which temporarily excites or inhibits a certain brain area. It is thought that tinnitus is generated in the brain as a result of functional reorganization of auditory neural pathways and…
Authors hypothesized that the physical extracorporeal shock wave (ESW) stimulation will decrease the resting muscle activity of paralysed forearm muscles, reducing the degree of spasticity in surface electromyography examination as well as Modified…
We hypothesize that monomeric and oligomeric flavanols (MOF) have a beneficial effect on renal-endothelial function in the dietary management of T2D, as reflected by improvement of AER and renal-endothelial biomarkers.
In euthyroid women with thyroid autoimmunity and recurrent miscarriage, levothyroxine started preconceptional, increases live births beyond 24 completed weeks by at least 20%, compared to placebo.
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
Saphenus blok reduceerd opname duur na epifysiodese van de knie - een triple blind superiority trial
We hypothesize that a single shot saphenous nerve block in combination with general anesthesia would be superior to general anesthesia alone regarding opiod consumption. pain scores. recovery and length of stay in adolecent patients undergoing…
90-day treatment with a selected probiotics mixture can reconstitute the microbiome diversity after antibiotic treatment for community-acquired pneumonia.
Recent research shows that obesity is associated with changed bowel flora composition with a relative abundance of the two dominant bacterial divisions, the Bacteroidetes and the Firmicutes. Interestingly, this specific bacteria associated condition…
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
1. Volume intervention by a diuretic and moderate sodium diet potentiates the antiproteinuric effects of aliskiren in patients with residual albuminuria during conventional RAAS-blockade; 2. Aliskiren neutralizes the reactive rise in plasma renin…
It is hypothesized that tianeptine will prevent alfentanil‐induced respiratory depression without affecting antinociception.
N/A
Patients who received CBM-I training will start their exposure therapy with lower anxiety levels, and their anxiety levels will reduce faster compared to patients that receive a placebo training.
Cholesterol lowering by low fat diet and lovastatin will also reduce very long chain fatty acids in patients with X-ALD.
This study will investigate the best treatment of Delayed Sleep Phase Syndrome (melatonin, placebo or melatonin and light therapy), and will determine whether patients with ADHD and DSPS have blood values that may indicate susceptibility for chronic…