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We hypothesize that BCG vaccination may reduce hospital admission and improve the clinical course of symptoms of elderly people during the SARS-CoV-2 outbreak.
2gr of Cefazolin is effective as prophylaxis for surgical site infections following implant removal below the level of the knee.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status, which will eventually reduce the risk of coronary calcification.
The objective of the study is to evaluate safety, tolerability, and pharmacokinetics (PK) of ALKS 6610 after single ascending oral doses in healthy adult subjects.
We expect that metformin in combination with lifestyle interventions reduces Antipsychotic induced Weight Gain compared to placebo in combination with lifestyle interventions.
We hypothesize that GABA could improve glucose tolerance and cardiovascular health after long-term supplementation
OTL78 is safe for use in healthy male individuals and patients with prostate cancer. OTL78 binds to malignant prostate tissue and malignant lymph nodes.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
Although the immunomodulatory effects of HCQ and CQ have been well described in isolated cell subsets in vitro, there is a lack of clinical studies describing the immune response after HCQ treatment in humans. In this clinical study we therefore aim…
We hypothesize that the combination of LEF/HCQ significantly and safely inhibits activity of primary Sjögren’s syndrome and molecular fingerprints will allow prediction of therapy response as well as identification of pathways that confer lack of…
We hypothesize that oxytocin administration will enhance the effectiveness of the Cardiff Emotion Recognition Training
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.
Predominantly sleeping in the non-supine position could improve oxygenation and thereby shorten the disease course in admitted COVID-19 patients.
1) It is expected that the percentage of days abstinent will be higher in both training interventions compared to the sham ApBM with religion-adapted ApBM having the biggest effect-size in this comparison. Also, it is expected that participants with…
The pericapsular nerve group (PENG) block is superior to placebo 'sham' blocks in hip arthroplasty surgery in reducing patients pain scores (Numeric Rating Scale of 0 to 10), on the day of surgery
To investigate whether augmentation of one standardized exposure session for SAD with tVNS has beneficial effects compared to sham enhanced exposure by examining subjective anxiety during exposure. Subjective anxiety will be measured with ‘…
This study will investigate the potential of EDP1815 to modify the immune system through a Keyhole Limpet Haemocyanin (KLH) challenge. Furthermore, safety and tolerability of multiple oral doses of the monoclonal microbial EDP1815 will be assessed…
We expect to find differences between the intervention groups and control group (in favour of the intervention groups) on behaviour, quality of life, well-being and communication behaviour scores in nursing home residents with dementia and distress…
The study hypothesis is that the LSD group shows an increase in positive mood and subjective effects between baseline and follow-up after 4 weeks of repeated dosing with LSD compared to the placebo group. An additional study parameter is the…