4546 resultaten
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
Consumption of the new developed GUM will decrease the incidence of upper respiratory tract infections (URTI) and/or decrease the duration of acute gastrointestinal tract infections (GITI) in Asian toddlers
Unlike other potential sepsis treatments, Alkaline Phosphatase has been shown to act at the front end of the inflammatory cascade. By doing so, it eliminates the root cause of the SIRS, and prevents the progression into sepsis and septic shock.
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Better and faster recovery of arm/hand for patients treated with rTMS
We hypothesize that UDCA on top of ezetimibe leads to an increased cholesterol excretion via the feces by stimulating ABCG5/8 and preventing absorption of cholesterol due to blocking NPC1L1 and therefore promoting elimination of cholesterol from the…
The use of atorvastatin in persons at high risk of RA is associated with a reduction in de development of arthritis
Is there a diiference in antidepressant efficacy between ECT and a combination of ECT and nortriptyline? Does combination therapy with ECT and nortriptyline result in a faster antidepressant response compared with ECT monotherapy? Does combination…
We hypothesize that participants in both groups improve on cognitive functioning after the intervention period, and that participants who will receive CIRCuiTS in combination with active tDCS will improve more than the participants who receive…
Inhalation of rhDNase before sleep increases the expiratory flow at 25% of the actual forced vital capacity (MEF25) compared to inhalation of rhDNase in the morning.
THC causes changes in resting state brain activity that can be visualized by fMRI
Intrathecal methylprednisolone reduce the features of central sensitization in patients with complex regional pain syndrome type 1 having symptoms longer than 6 months and shorter than 6 years.
Etanercept is able to improve clinical and functional abnormalities and to halt or reverse radiographic changes in inflammatory erosive hand osteoarthritis by virtue of blocking a major pro-inflammatory cytokine, tumor necrosis factor (TNF).
Ocular surface inflammation plays a pivotal role in dry eye and possibly in blepharitis. We hypothesize that the quantity of pro-inflammatory cytokines in tears and the expression of markers of inflammation on conjunctival cells are increased in…
Imiquimod, an immunomodulator, has been shown safe and effective in the treatment of external genital warts caused by low risk human papillomavirus (HPV). Therefore, it is hypothesized that this topical treatment may also be effective against…
Lithium treatment potentially enhances survival and slows disease progression in ALS patients
To evaluate the safety and tolerability of AP30663 in healthy males at doses up to 12mg/kg
2gr of Cefazolin is effective as prophylaxis for surgical site infections following implant removal below the level of the knee.
To investigate the effect of low dose oral silicon as an adjunct to calcium/vitamin D3 on markers of bone turnover and BMD.
Acute stress and increased levels of dopamine in the brain will lead to a shift from goal-directed behaviour to habitual behaviour. The shift will coincide with a change in functional connectivity between brain areas governing goal-direct and…