187 resultaten
A slow and unpredictable deterioration of the capabilities of the older patient can lead to a vulnerable situation, often unnoticed by the caregiver. As a consequence, care is delayed and acute problems will arise that will need an immediate…
The COL3A1 polymorphism is a inheritable genetic defect, responsible for the increased susceptibility to pelvic organ prolapse in women.
1. Prosthetic valve characteristics (type; location; size resulting in the presence/absence of PPM) are related to functional outcome and quality of life; 2. The incidence/spectrum of prosthetic valve-related complications in adults with CHD differs…
We hypothesize that exercise training improves maximal exercise capacity in adult patients with a systemic RV. Moreover, we hypothesize that exercise training decreases serum NT-proBNP levels and increases quality of life in adult patients with a…
The aim of this protocol is twofold. 1. Firstly, we aim to combine the new response monitoring method (PET imaging) with the present technique (dynamic CE-MRI imaging) in order to discriminate between favourable and unfavourable response of the…
1. In Barrett Esophagus (BE), probe-based laser endomicroscopy (pCLE) provides better correlation with the histological diagnosis compared to detailed inspection with Narrow Band Imaging (NBI), reducing the high rate of false-positive findings with…
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MRI leads to higher prostate cancer detection: MR guided prostate biopsy and MR-ULtrasound Fusion Guided prostate biopsy will yield higher detection rates in comparison to Transrectal Ultrasound guided prostate biopsy.
Cancer is a serious and potentially fatal disease. Scientific studies indicate that good social support is of great imporance for physical and emotional well being. At the same time there is little knowlegde about what specific social reactions are…
A hinged external elbow fixator may provide enough stability to start early mobilization after ORIF and/or arthroplasty (of the radial head) of complex dislocations with residual instability. Our hypothesis is that early mobilization will prevent…
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
The hypothesis to be tested is that the efficacy and toxicity of treatment with 90Y-ibritumomab tiuxetan meets the expectations as described in the protocol.
Long-term use of 6-thioguanine is more hepatotoxic, based on histopathological findings, as compared with the long-term use of azathioprine and 6-mercaptopurine in inflammatory bowel disease patients.
The aim of this study is to assess barriers and facilitators of implementation of external cephalic version in The Netherlands, and to develop an innovative implementation strategy based on improved patient counselling and information of health care…
Duogestan® leidt in symptomatische, vroeg postmenopausale vrouwen tot een verbetering in kwaliteit van leven van 20%.
A lightweight monofilament polypropylene mesh in a sublay position reduces the incidence of a parastomal hernia.
The 6minute walk run test is reproducible, valid and has a higher responsiveness as the 6 minute walk test in patients with a heart disease.
Cancer patients who develop thrombosis have a worse prognosis than cancer patinets without thrombosis. There is evidence that activation of the coagulation cascade increases tumor growth and angiogenesis. Therefore the objective is to find a marker…
The application of the haemostatic device, ACF-matrix haemostat will reduce blood and fluid loss from the LIMA bed after CABG surgery.
This pilot study hypothesizes that ICG enhanced near-infrared fluorescence (NIRF) optical imaging enables the intra-operative detection of breast carcinoma in breast cancer patients.