643 resultaten
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
Primary hypothesis: Octane concentrations in exhaled breath facilitate early detection of ARDS in ICU patients. Secondary hypotheses: - ARDS resolution is associated with a decrease in octane in exhaled breath. - Additional biomarkers of ARDS can be…
We hypothesize that PARP inhibitors can potentiate radiation-induced tumor cell death in patients treated with PRRT. To determine the maximin tolerated dose (MTD) of this combination, a phase 1 dose-escalation study is needed.
Null hypothesis: the 8 centres with different cardiac rehabilitation (CR) programmes do not differ from each other with regards to the effectiveness.
The natural experiment of COVID-19 related governmental measures of home confinement and social distancing has led to a decrease in physical activity levels of school going adolescents of Punjab, India.
It is hypothesized that taste and smell disturbances are common among GIST patients using TKIs.
DBS leads to a symptom reduction in patients with OCD
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
To test whether implementing a bundle of specific measures during the night shifts at the A&E department improves sleep quality and general physical and psychological well-being Investigate whether this bundle of measures 6 months after…
To investigate the feasibility and safety of the DMUA-HIFU system for treatment of atherosclerotic plaques.
We hypothesize that MTX can be quantified in semen and that it is associated with measures of semen quality and DNA fragmentation
Individuals at the top 20% of genetic risk distribution for glaucoma are at a higher relative risk for having glaucoma.
Non-inferiority of tsDAMRD first versus TNFi first in terms of ACR50 response at 12 weeks
Primary sclerosing cholangitis (PSC) is a severe liver disease of unknown etiology leading to fibrotic destruction of the bile ducts and ultimately to the need for liver transplantation (LTx) in young adults. When PSC develops before the age of 13…
The aim of this present diagnostic study is to determine the accuracy by which we can detect residual disease after neoadjuvant chemoradiotherapy.
Submucosal irrigation with the Gum Irrigator will reduce bleeding on probing, pocketdepts and the amount of anearobic bacteria in the non-surgical treatment of peri-implantitis.
Food provision does not match food consumption. The amount of protein in consumed hospital meals is below current protein requirements.
Too little is known about patient preferences on (self management) education during the 4 to 6 weeks after total knee replacement surgery. We hypothesise this study will provide us with valuable insights on their preferences: type of information (…
Non invasive hemodynamic monitoring is as good as invasive monitoring
We hypothesize that the HINTS+ test is more reliable than early MRI imaging in patients with acute onset continuous dizziness. As a result it is hypothesized that HINTS+ clinical examination leads to lower costs and an improvement in Quality of Life…