280 resultaten
A 10% point difference between the experimental groups and control group in MPV uptake is expected.
The main aim of the proposal is to study the processes involved in non-chronic vs. chronic drug seeking behavior in samples of alcohol dependent persons (ADs) and pathological gamblers (PGs) with different levels of chronicity. We thereby rely on…
Botulinum toxin A declines the severity of tardive dyskinisias.
We hypothesize that general practitioner (GP) involvement improves both aftercare and preventive care resulting in improved quality of life and patients’ satisfaction. Furthermore, a GP-led recurrence detection program leads to at least equal…
To evaluate variations of androgenicity and androgen (re) activity in (apparently) eugonadal women by using CAG repeat length polymorphism ([CAG]n) of the androgen receptor, free testosterone levels, 2D:4D ratio and attention for erotic stimuli (…
Reduced numbers of specific CD8+ T cell subsets in frailty elderly correlate with a limited ability to mount robust mucosal T cell responses to control and clear respiratory infections
Inflammatory injury of the lung after cardiac surgery in heart failure versus non-heart failure patients; An observational study of clinical variables, genetic association, and etiologic and prognostic aspects of inflammatory markers in serum and…
A self-management program including self-treatment of exacerbations, leads to a reduction in the severity and duration of exacerbation compared to a similar self-management program without these self-treatment guidelines in hospital out-patients…
We will establish the optimal dose chloroprocaine for knee-arthroscopy
1. Flat adenomas are common findings in patients at average- or at high-risk for CRC; 2. Flat adenomas are characterized by a different molecular profile as compared to polypoid lesions; these molecular features are associated with an increased risk…
Information on the dynamics and shape of the stent graft and stented target vessels, and how these change over time will improve our understanding about the fixation and/or sealing of the stent graft, which may help in stent graft selection and in…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
To investigate the possibility to predict chemotherapy response using proliferation assays.
Combination of a round window insertion approach and a lateral wall electrode array minimizes insertion trauma
Octreotide, a somatostatin analog that preferentially binds with sst2, is frequently used in the treatment of somatotropic pituitary adenomas and neuroendocrine tumors. The glucocorticoid-mediated sst2 downregulation in corticotroph adenoma cells…
1. We expect the ST/SPSP-50 condition to be more effective than ST/SPSP-25 condition on depression outcome and/or characterological symptoms. 2. No differences in outcome are expected between ST en SPSP and we don’t expect the type of treatment to…
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
the prognosis of patients with severe RV failure after LVAD-implantation, post-cardiotomy or post-MI is grim, as medical treatment options are scarce. In a previous study, treatment with the Impella RP has been proven to be safe, feasible and…