19 resultaten
We expect brain activity and brain reactivity to change as satiation progresses. ROI are : Brainstem (dorsal vagal complex (DVC), nucleus tractus solitarius (NTS), parabrachial nucleus (PBN)), Hypothalamus, Insula, overlying operculum, secondary:…
We hypothesize that a conversation aid and information brochure for patients, and a communication training for physicians improves satisfaction and quality of the discussion about potential treatment restrictions at the internal medicine outpatient…
Adolescence represents a crucial stage in the maturation of executive functioning (e.g. working memory and inhibition) and mental health (i.e. behavioral and emotional functioning, and self-concept), which both are important predictors of academic…
Salt restriction is an effective strategy to attenuate or prevent VEGF inhibitor-induced toxicity, primarily the rise in blood pressure.
After initiation of anticoagulant therapy in females diagnosed with DVT or PE in their fertile age, 30% of patients will develop abnormal menstrual bleeding leading to decreased quality of life.
1. Straatwijzer 2.0 leads to improvements in the knowledge of youths with mild intellectual disabilities (MID) and their parents about the characteristics of their MID, and about the frequently occurring psychiatric disorders ADHD, autism, conduct…
The overall aim of this study is to implement bariatric surgery including the multidisciplinary care pathway around the procedure for unsuccessfully treated adolescents with severe obesity in the Netherlands. Therefore, feasibility, efficacy and…
Addition of alternative tests (TEG/ROTEM® and/or TGA) which reflect the whole hemostatic status of a patient might help recognizing the level of thrombin formation and fibrinolysis and improve care in ECMO patients and potentially reduce the risk of…
We hypothesize that anxiety symptoms worsen after follow-up imaging compared to patients baseline anxiety levels.
1. Using a wobble cushion and tangle will lead to improved performance on a math test, reading comprehension test and on a sustained attention test for children with more problems with sensory information processing (both low and high threshold) in…
We hypothesize that by combining the recently validated gout flare criteria with a patient-friendly app and real-time monitoring, we can implement a gout flare measure that is less prone to recall bias and can be used by patients at home. It could…
Multiple sclerosis (MS) is a brain disease, in which myelin sheaths in the brain and spinal cord are damaged. If repair of myelin damage is incomplete, nerve terminals will be irreversibly destroyed, leading to neurological symptoms. Ineffective…
Enhanced endoscopic imaging, including high-definition white light endoscopy and virtual chromoendoscopy, alongside targeted biopsies provides an accurate and reproducible assessment of chronic atrophic gastritis disease extent and staging, when…
We hypothesise that among babies admitted to primary care birth centres: 1. Non-invasive screening for neonatal jaundice will (cost-)effectively reduce the incidence of severe hyperbilirubinaemia. 2. Should treatment for hyperbilirubinaemia be…
The use of ECLS can lead to systemic inflammatory response. It is likely that ECLS affects red blood cell and platelet function after its initiation, the time course of these changes and their clinical relevance is yet unclear.
Neuropsychiatric symptoms (e.g. apathy, depression, anxiety, agitation) are very common in patients with Mild Cognitive Impairment (MCI) and Alzheimer’s disease (AD) and are negatively related to various clinical outcomes. However, despite growing…
Can imaging surveillance frequency be safely reduced in a select group of EVAR patients, i.e. patients with an asymptomatic infrarenal abdominal aortic aneurysm (AAA) that underwent EVAR without abnormalities on the initial postoperative CTA.
Targeted Next Generation Sequencing (NGS) can distinguish benign pancreatic diseases, such as pancreatitis, from pancreatic malignancies during the diagnostic proces of patients with an uncertain diagnosis and treatment plan.