21 resultaten
The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…
To determine the epidemiology, diagnosis and prognosis of enterovirus (EV) and parechovirus (HPeV) infection in Dutch children. Hypotheses: 1. EVs are one of the most important viral agents of infection in Dutch children; 2. EVs are the major cause…
Develop a screening tool to identify children at risk of posttraumatic stress disorder after an accident.
For patients with breast cancer who are not applicable for breast-saving treatment (because of tumor characteristics), who prefer an amputation or who undergo a prophylactic amputation an immediate breast reconstruction is a standard offer. A…
Patients with lymphoma who are treated with rituximab have an increased risk of developing infections. However because of the disease, and because rituximab also diminishes healthy B cells, the humoral response to vaccination may be impaired.
Early recognition of deteriorating patients is key to possible effectiveness of an RRS. Therefore, phased introduction of the afferent limb (aimed at detection) followed up by the implementation of the efferent limb (the Medical Emergency Team) will…
We hypothesize that the WavSTAT optical biopsy system may improve the endoscopists ability to detect and distinguish suspicious lesions in the Barrett oesophagus, while reducing the need for extensive biopsy protocols during surveillance endoscopies…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
Octreotide, a somatostatin analog that preferentially binds with sst2, is frequently used in the treatment of somatotropic pituitary adenomas and neuroendocrine tumors. The glucocorticoid-mediated sst2 downregulation in corticotroph adenoma cells…
We hypothesize that Moroccan-Dutch differ from native-Dutch in stress reactivity. This difference is not explained by group differences in known non-social risk factors for psychosis. Affirmative findings in the current study would support to the…
Specific areas of language production are affected in children and adolescents with classic galactosemia, in particular syntactic production. Further, it is hypothesized that the galactosmic patients will show a profile of general cognitive…
1. All obese patients have low-grade systemic inflammation characterized by IL-6, TNF-alfa, leptin and adiponectin. Patients with obesity and asthma have higher expression of these mediators and neutrophils in bronchial mucosa than obese patients…
Early diagnosis of cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) combined with swift identification and treatment of pulmonary infections is important for the preservation of pulmonary function, quality of life and life expectancy. A…
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
To assess the effectiveness of the Xience stent compared to the CYPHER stent in the PCI treatment of all patients in the MCL during 2007- 2008. This study runs parallel with the XAMI study.
Efficacy of occlusion therapy initiated in patients with untreated amblyopia between twelve and forty years of age is effective.
The fenestrated Anaconda endograft is safe for durable exclusion of juxta and suprarenal AAA.
Show accurate and proper functioning of the Medimate MiniLab system for professional and self test use.The objective of the studies is to show the performance of 10% or 0.1 mmmol/l @ 95% confidence interval.