149 resultaten
Primary hypothesis is whether patients with a PTSD the distraction of a positive emotional valence will be more effective in decreasing the vividness and emotionality of a traumatic memory compared to distraction with a neutral task or exposure only…
Since probenecid is a potent multi UGT inhibitor, endoxifen concentrations may be significantly (and clinically relevantly) increased when administered concomitantly with probenecid.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
We hypothesize that especially the reward centres of the brain respond much stronger to processed food in BED, whereas much smaller differences are expected after consuming unprocessed food.
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
We hypothesize that giving feedback to healthcare providers on the performance of their own hospital improves processes of care and leads to better outcomes.
Darolutamide (Nubeqa) is a novel androgen receptor antagonist drug for the treatment of non-metastatic castration resistant prostate cancer (CRPC), approved by the FDA and EMA. It does not inhibit major CYP enzymes or major transporters at…
It is expected that differences in energy density of the study products will modulate the protein digestion profile of dairy proteins in elderly
In the first of two substudies, we test the hypothesis that in healthy individuals without ELS, hydrocortisone will be effective in enhancing stress adaptation and extinction learning in an experimental model of exposure therapy, while it is not in…
Golimumab 100 mg every 1,5 month has similar trough levels to golimumab 50 mg every month; golimumab 100 mg every 2 months has a similar AUC to golimumab 50 mg every month.
Tumour cell disruption by radiation generates a surplus of neo-antigens that enhances the effect of immunotherapy in solid malignancies as well as malignant lymphomas. The hypothesis is that the combination of immune checkpoint inhibitors and…
De studie heeft als doelstelling de verschillen in maaglediging en eiwit opname van caseïne met verschillende productmatrix (mineralensamenstelling) te meten.
The higher hardness/protein density of protein gel would delay gastric emptying and protein hydrolysis in humans; MRI technique can used to monitor gastric digestion (in this case: protein hydrolysis) in humans.
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
We hypothesize that the MMP could be cost-efficient for a part of the patients, but that for some patients a more simple prosthesis would be more cost-efficient. Therefore, we do not expect big differences in cost-effectiveness between the MMP and…
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
Interaction between oral dexamethasone and aprepitant is different than the interaction between iv dexamethasone and aprepitant.
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
Which design of cognitive aid (emergency manual) is easier to use and results in less missed critical actions during anesthetic emergencies