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Intravesical instillation of BCG is a widely accepted strategy to prevent recurrence of non muscle invasive bladder cancer. The most accepted treatment schedule is induction of BCG: weeks 1 through 6 plus maintenance (weeks 1,2,3) at months 3,6 and…
We hypothesize that selfmanagement support via an internet based service in addition to usual care will improve health related quality of life in patients with severe asthma who have participated pulmonary rehabilitation in specialized asthma…
The hypothesis is that a 5-week perturbation-based training program using the Radboud Falls Simulator (RFS) will improve the mechanical efficiency of stepping to recover balance in community-dwelling persons in the chronic phase after stroke.
Glucose control in diabetic patients with end stage renal disease might be influenced by treatment with haemodialysis, but data on this subject are limited. Haemodialysis could affect glucose control through several mechanisms. It has been suggested…
The Veder Method can be succesfully implemented in daily care of elderly with dementia and leads to a higher quality of care, higher job satisfaction of the caregivers and greater patient satisfaction.
To determine the outcome of hand function of (ex)patients with flexor tendon rupture 7 – 10 years after surgical repair. We expect that subjects with flexor tendon injury have significantly worse hand function than healthy subjects.
The aim of this study is to correlate the score on a functional performance test battery to the occurence of ACL reruptures and contralateral ruptures. We hypothesize that athletes with a limb symmetry index of <100% on strength or hoptests…
The maternal diet is highly responsible for the composition of breast milk which will result in at least differences between cultures and geographical separated populations. The maternal diet and breastmilk composition will show off in the…
To assess the effect of an Amino Acid based Formula (AAF) with synbiotics on the balance of major constituents of the gut microbiota, specifically Bifidobacteria vs. Clostridial groups.
“Personalized Prevention Approach for CardioMetabolic Risk” (PPA CMR), a prevention program for cardiometabolic disease (CMD) combined with an individualized lifestyle intervention, is effectiveness and cost-effectiveness when implemented in primary…
We aim to test the hypotheses that offering additional online adaptive coaching to a web-based self-management program will be more effective than a web-based self-management program without coaching in terms of self-management behaviour without…
Endocuff colonoscopy will increase the number of adenomas detected.
Vernakalant is superior to Amiodarone and rate control alone in the acute conversion of recent onset atrial fibrillation (AF) in critically ill patients admitted to the medical ICU.
Primary: are there differences between the online course group and the control group in the change in depressive complaints from baseline to follow-up measurements? Secundary: Is the intervention cost-effective compared to a no preventive…
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
Comparison of CT-angiography and Transcranial doppler for the detection of cerebral vasospasm after aneurysmal subarachnoid hemorrhage
we would like to investigate whether multiple fecal transplantations using either allogenic (lean preferably vegetarian/vegan donor) or autologous (own) donors have a beneficial effect on non alcoholic steatohepatitis (NASH) using biopsy and MRI…
In this observation study we hypothise an incidence of UTIs of 30% in the first year after starting CIC. Moreover we hypothise a marked reduction in quality of life and an increase in health care expensis in patients with UTI.
Mindfulness training as well as medication will reduce symptoms of attention, hyperactivity and impulsivity, not only directly after training but also at follow-up.
It is possible to detect altered DNA from endometrial and ovarian cancer cells in the Pap-smear by analysing a set of predetermined genes