The proposed longitudinal study aims to examine1) if the onset of type 1 diabetes before vs. during puberty results in different outcomes of glycaemic control, self management, psychological functioning and diabetes-related QoL2) how the developmentā¦
Source
Brief title
Condition
- Other condition
- Glucose metabolism disorders (incl diabetes mellitus)
Synonym
Health condition
psychologisch functioneren, cognitieve vaardigheden
Research involving
Sponsors and support
Intervention
No registrations found.
Outcome measures
Primary outcome
Glycemic control (HbA1c) / Psychological functioning / Diabetes related Quality
of life and selfmanagement
Secondary outcome
Cognitive functioning / self esteem / autonomy / biological development
Background summary
Rationale: The DCCT/EDIC study has shown that strict glycaemic control during
adolescence decreases the risk of developing complications later in life, even
if this level of control is not maintained afterwards. However, the majority of
adolescents with type 1 diabetes are in poor control and so far medical or
psychological interventions have shown limited success. Adolescence is
characterized by major biological, cognitive, psychological and social role
changes and the complex interaction between these developmental trajectories,
and its impact on health outcomes, is still poorly understood. A specific topic
of interest in this context is the timing of diagnosis and how the cognitive
development relates to self management skills.
Study objective
The proposed longitudinal study aims to examine
1) if the onset of type 1 diabetes before vs. during puberty results in
different outcomes of glycaemic control, self management, psychological
functioning and diabetes-related QoL
2) how the development of cognitive skills of adolescents with type 1 diabetes
relates to their diabetes self management tasks and how this affects diabetes
outcomes.
Study design
Longitudinal, observational study
Study burden and risks
To examine the psychological and cognitive development of children with
diabetes throughout puberty, questionnaires and neuropsychological tests will
be used. Children with diabetes are already accustomed to filling out
questionnaires about their well-being in routine care. Completing the basic
questionnaire within this study will take approximately 10 minutes and be done
every 6 months for the 3 years of this study. We believe this won't be too much
of a burden.
The neuropsychological tests and additional psychological questionnaires will
take more time (appr. 3 hours) and could therefore be more of a burden. From
previous experiences within our department, we know that children don't object
to the tests and even like the 'games'. In this study, 4 tests will be assessed
over the 3 years.
The physical measures (HbA1c, complication screening etc) are part of the
routine care, no extra physical assessments are necessary for this research.
A selection of children will be interviewed about their eating behaviour. Time
and place will be up to the children to minimize the burden.
Van der Boechorsstraat 7
Amsterdam 1081 BT
NL
Van der Boechorsstraat 7
Amsterdam 1081 BT
NL
Listed location countries
Age
Inclusion criteria
Type 1 diabetes, age 8-15 years
Exclusion criteria
Not fluent in Dutch and mental retardation
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL41105.029.12 |