Objective:1. To describe the prevalence and incidence of *difficult-to-treat* adult asthma in the Netherlands.2. To describe factors associated with adherence with pulmonary medication in patients with difficult-to-treat airway disease. 3. To…
Source
Brief title
Condition
- Respiratory disorders NEC
Synonym
Research involving
Sponsors and support
Intervention
No registrations found.
Outcome measures
Primary outcome
Main study parameters/endpoints:
Study 1: the prevalence and incidence of patients with difficult-to-treat
asthma (cases/10.000 inhabitants) in the Netherlands.
Study 2: factors associated with adherence to pulmonary medication in
difficult-to-treat asthma.
Study 3: inhalation technique scores in adherent patients with
difficult-to-treat asthma
Study 4: To assess the prevalence of patients with truly severe, refractory
asthma and describe the characteristics of these patients
Secondary outcome
not applicable
Background summary
Rationale:
Patients with severe refractory asthma pose a major healthcare problem. It has
become increasingly clear that, for the development of new targeted therapies,
there is an urgent need for further characterisation and classification of
these patients. However, the exact prevalence of patients with severe
refractory asthma is unknown and in addition to this, the question remains if
patients who have difficult-to-treat asthma have truly severe refractory asthma
or are not adherent with their medication or have an incorrect inhalation
technique. Data on this is lacking.
Study objective
Objective:
1. To describe the prevalence and incidence of *difficult-to-treat* adult
asthma in the Netherlands.
2. To describe factors associated with adherence with pulmonary medication in
patients with difficult-to-treat airway disease.
3. To describe the inhalation technique in adherent patients with
difficult-to-treat airway disease.
4. To compare patients* characteristics of patients with difficult-to-treat
asthma with optimal treatment adherence and adequate inhalation technique and
severe controlled asthma with optimal treatment adherence and adequate
inhalation technique.
Study design
Study design:
Descriptive observational study
Study burden and risks
There are no risks involved.
Patients* asthma will be assessed by means of a asthma control questionnaire
and, if not controlled, their general practitioner will be informed for follow
up. Also a selection of the patients will be asked for inhalation instructions
which might benefit the overall intake of inhalation medication.
Meibergdreef 9
1105 AZ
NL
Meibergdreef 9
1105 AZ
NL
Listed location countries
Age
Inclusion criteria
All patients registerd in the 73 participating pharmacies using inhaled corticosteroids
Exclusion criteria
patients with COPD will be excluded
Design
Recruitment
Followed up by the following (possibly more current) registration
No registrations found.
Other (possibly less up-to-date) registrations in this register
No registrations found.
In other registers
Register | ID |
---|---|
CCMO | NL37637.018.11 |